Results 151 to 160 of about 1,895,969 (377)

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

open access: yesFEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti   +8 more
wiley   +1 more source

An Intelligent Feature Concatenation Process-Based Effective Query Expansion for Patent Retrieval Approach Using Optimal Bi-clustering and Enhanced Social Engineering Optimizer

open access: yesInternational Journal of Computational Intelligence Systems
The major objective of patent retrieval is to identify relevant documents from a large database. Patent retrieval requests often take the form of patent claims, as in prior art searches, and these searches typically require a long time to complete ...
G. David Raj   +3 more
doaj   +1 more source

An information-theoretic approach to automatic query expansion [PDF]

open access: green, 2001
Claudio Carpineto   +3 more
openalex   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

open access: yesFEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee   +3 more
wiley   +1 more source

Searching biomedical ontologies based on content [PDF]

open access: yes, 2007
As more ontologies become publicly available, finding the 'right' ontologies becomes much harder. In this paper, we introduce a new ontology search technique which is based on corpus analysis.
Alani, Harith   +4 more
core  

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Query Expansion Techniques for the CLEF Bilingual Track [PDF]

open access: green, 2002
Fatiha Sadat   +3 more
openalex   +1 more source

User - Thesaurus Interaction in a Web-Based Database: An Evaluation of Users' Term Selection Behaviour [PDF]

open access: yes, 2001
A major challenge faced by users during the information search and retrieval process is the selection of search terms for query formulation and expansion.
Revie, C.W., Shiri, A.A.
core  

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

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