Results 221 to 230 of about 3,622,651 (382)

CRCFound: A Colorectal Cancer CT Image Foundation Model Based on Self‐Supervised Learning

open access: yesAdvanced Science, EarlyView.
CRCFound is a self‐supervised learning‐based CT image foundation model for colorectal cancer (CRC). Pretrained on 5137 unlabeled CRC CT images, it learns universal feature representations, enabling efficient adaptation to various clinical tasks. The model demonstrates outstanding performance and generalization across multiple diagnostic and prognosis ...
Jing Yang   +13 more
wiley   +1 more source

SQLizer: query synthesis from natural language

open access: yesProc. ACM Program. Lang., 2017
Navid Yaghmazadeh   +3 more
semanticscholar   +1 more source

USP10 Inhibits Ferroptosis via Deubiquinating POLR2A in Head and Neck Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
This study identifies USP10 as a novel deubiquitinase that antagonizes ferroptosis in head and neck squamous cell carcinoma (HNSCC). Mechanistically, USP10 directly stabilizes POLR2A protein through post‐translational deubiquitination, enabling POLR2A‐mediated transcriptional activation of SLC7A11, a key ferroptosis inhibitor.
Diekuo Zhang   +13 more
wiley   +1 more source

Genetic Deconvolution of Embryonic and Maternal Cell‐Free DNA in Spent Culture Medium of Human Preimplantation Embryo Through Deep Learning

open access: yesAdvanced Science, EarlyView.
DECENT is a deep learning method that enhances noninvasive preimplantation genetic testing by accurately reconstructing embryonic copy number variations (CNVs) from cell‐free DNA in spent embryo culture media. By mitigating maternal contamination, DECENT improves diagnostic accuracy, even with high contamination levels, offering a reliable, noninvasive
Zhenyi Zhang   +3 more
wiley   +1 more source

An Allele of Glutamate Formiminotransferase Triggers 5‐Methyl‐Tetrahydrofolate‐to‐MeFox Conversion and Facilitates Folate Biofortification in Maize

open access: yesAdvanced Science, EarlyView.
This work demonstrates the distinct roles of the glutamate formiminotransferase (GFT) enzyme in plants. The GFT triggers the conversion of 5‐methyl‐tetrahydrofolate to MeFox in plants, a process distinct from its role as a formiminotransferase in mammals.
Tong Lian   +15 more
wiley   +1 more source

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