Results 151 to 160 of about 168,099 (309)

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

IMTKU Question Answering System for World History Exams at NTCIR-12 QA Lab2

, 2016
In this paper, we describe the IMTKU (Information Management at Tamkang University) question answering system for Japanese university entrance exams at NTCIR-12 QA Lab-2. We proposed a question answering system that integrates natural language processing
Day, Min-Yuh;Tsai, Cheng-Chia;Chuang, Wei-Chun;Lin, Jin-Kun;Chang, Hsiu-Yuan;Sun, Tzu-Jui;Tsai, Yuan-Jie;Chiang, Yi-Heng;Han, Cheng-Zhi;Chen, Wei-Ming;Tsai, Yun-Da;Lin, Yi-Jing;Lin, Yue-Da;Guo, Yu-Ming;Chien, Ching-Yuan;Lee, Cheng-Hung
core  

EXPRESSION OF CONCERN: A Newly Identified 45‐kDa JAK2 Variant with an Altered Kinase Domain Structure Represents a Novel Mode of JAK2 Kinase Inhibitor Resistance

Molecular Oncology, EarlyView.
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Early Recognition of Treatment‐Responsive Rapidly Progressive Dementia: The Modified STAM3mP Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Early identification of patients with treatment‐responsive rapidly progressive dementia (RPD) is important as early treatment improves outcomes. The STAM3P score identifies treatment‐responsive RPD using “high risk” presenting features. We optimized performance by adding a time component (i.e., dementia within 3 months) and validated the ...
R. W. van Steenhoven, N. Satyadev, A. E. M. Bastiaansen, Y. D. Piura, J. Kerstens, Y. S. Crijnen, J. Brenner, T. Brand, T. M. Bienfait, S. Veenbergen, J. M. de Vries, F. J. de Jong, E. G. P. Dopper, P. A. E. Sillevis Smitt, H. Seelaar, G. S. Day, M. J. Titulaer   +16 more
wiley   +1 more source

Question Answering Systems in Education and their Classifications

The paper studies Question Answering Systems that can be used in education as an engine to search for learning and/or other useful information. A wide set of different Question Answering Systems, such as START, Wolfram|Alpha, AllExperts, etc.
Zaiceva, Larisa, Jakovļeva, Olga
core   +1 more source

Clarification Dialogs: a tool for Question Answering disambiguation,

, 2007
We present a Question Answering system that provides a natural lan- guage interface to Databases. Our system uses clarification dialogues in order to disambiguate the possible meaning of user questions in natural language.
Quintano, Luis, Rodrigues, Irene Pimenta
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A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley   +1 more source

Advancing Stroke Clinical Trials Using Community Engagement and Implementation Science Approaches

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Stroke clinical trials are essential for advancing stroke care but can face challenges with recruitment, retention, clinical relevance, and translation into real‐world practice. We propose that integrating community engagement and implementation science approaches into stroke trials can help address these needs.
Lesli E. Skolarus, Devin L. Brown, Bernadette Boden‐Albala   +2 more
wiley   +1 more source

Question Answering : CNLP at the TREC-9 Question Answering Track

, 2000
This paper describes a question answering system that automatically finds answers to questions in a large collection of documents. The prototype CNLP question answering system was developed for participation in the TREC-9 question answering track.
Liddy, E. D., McCracken, N., Liu, X., Wang, H., Ozgur Yilmazel, Diekama, Anne R., Hudong Wang, Elizabeth D. Liddy, Chen, J., Nancy Mccracken, Xiaoyong Liu, Anne Diekema, Jiangping Chen, Yilmazel, O.   +13 more
core   +1 more source