Results 31 to 40 of about 16,743 (251)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
A Forensic Approach in the Determination of Sequence of Strokes using Fluorescence Spectrometry
Background: Fluorescence Microscope is a promising analytical method for the examination of the sequence of strokes of writing inks of different colours, brands, and models in a questioned document. Aims and Objectives: In the present article, an attempt
Vartika Khare, Anu Singla, Pawan Gupta
doaj +1 more source
Analysis of questioned documents: A review
During the last years (2000-2014), many publications concerning the forensic analysis of questioned documents have been published, and new techniques and methodologies are nowadays employed to overcome forensic caseworks. This article reviews a comprehensive collection of the works focused on this issue, including dating studies, the analysis of inks ...
Calcerrada Guerreiro, Matías +1 more
openaire +3 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
This work seeks to establish continuities and ruptures between the discourses related to the war in Afghanistan by intellectuals, politicians, and soldiers.
Tomás Leyton
doaj +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Institutionalization of the Lithuanian Council of Lords
The article deals with the problem of the Lithuanian Council of Lords institutionalization on the basis of the analysis of legal documents and everyday office work of the principality.
Krasinski Ivan Viktorovich
doaj
Assessing the Possibility of Identifying the Chronological Sequence of Superimposed Printed and Handwritten Lines in Counterfeit Documents Produced by Various Printing Machines and Rollerball Pens. [PDF]
Background: In forensic science, it is difficult to prove that questioned documents are authentic. One common way to commit document fraud is to change the original information by adding printed or handwritten strokes on top of it.
Nesrine Mahmoud +3 more
doaj +1 more source

