Results 201 to 210 of about 5,196 (282)

Single‐Sequence Deep Learning Delivers Crystal‐Quality Models of Covalent K‐Ras G12 Hotspot Complexes

IUBMB Life, Volume 78, Issue 6, June 2026.
ABSTRACT Structure‐based design of covalent drugs has achieved tremendous success by understanding and leveraging the three‐dimensional interactions between small‐molecule drug candidates and their protein targets. However, this approach traditionally relies on high‐resolution co‐complex structures obtained by X‐ray crystallography, NMR, or cryo‐EM ...
Sungwon Jung, Qinheng Zheng, Kevan M. Shokat   +2 more
wiley   +1 more source

Decision Threshold Setting in Binary Classification Problems—A Behavioral Lens

Journal of Operations Management, Volume 72, Issue 4, Page 536-555, June 2026.
ABSTRACT When binary classification models are wrong, managers face misclassification costs. Although false positive outcomes imply unnecessary mitigation efforts, false negative outcomes imply overlooking the class of interest. Humans calibrate these ai models supporting operational systems by adjusting the decision threshold that translates ...
Patrick Moder, Kai Hoberg, Felix Papier
wiley   +1 more source

Gaussian Process Regression for Tail Vehicle Departure Time Prediction at Signalized Intersections Using UAV Trajectory Data. [PDF]

Sensors (Basel)
Lu K, Liu Z, Zhang R, Xia Q, Wang R.
europepmc   +1 more source

Diagnostic Accuracy of Cervical Auscultation for Aspiration Detection in Adult Dysphagia: Implications for FEES Prioritization

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 3, June 2026.
ABSTRACT Objective(s) To determine whether cervical auscultation (CA) provides a high‐specificity, rule‐in bedside signal to prioritize fiberoptic endoscopic evaluation of swallowing (FEES) in adults at risk of aspiration. Methods Single‐center, cross‐sectional diagnostic‐accuracy study in a tertiary hospital.
Nisreen Naser Al Awaji, Abdullah Mohammed Alfaris, Shaden Abdulmohsen Alabdulkarim, Lama Al Bashir, Wajd Dhafer Alqahtani, Haya Saleh Aldahmash, Rawan Yahya Alshareef, Lara Nawaf Almutairi, Rawabi Mesfer Alqahtani, Hajar Abdulaziz Almuqrin   +9 more
wiley   +1 more source

Optimizing Cardiac Inpatient Flow and Resource Allocation in Low‐Resource Settings Using Queuing Theory: Insights From a Tertiary Hospital in Bangladesh

Public Health Challenges, Volume 5, Issue 2, June 2026.
This study applies queuing theory models (M/M/c/c and M/M/c/K) to optimize inpatient flow and resource allocation in the cardiology department of Sylhet MAG Osmani Medical College Hospital, Bangladesh. Using data from 6,277 patients in 2023, it identifies bottlenecks in CCU and PCCU, highlights bed shortages and overcrowding, and proposes reallocating ...
Md. Borhan Uddin, Khalidur Rahman, Md. Asaduzzaman, Sabbir Tahmidur Rahman, Md. Sabbir Hossain, Md. Shihab Mostafa   +5 more
wiley   +1 more source

Queueing Theory

, 1996
Denis Bosq, Hung T. Nguyen
openaire   +4 more sources

Association of insomnia, insulin resistance traits, and cardiovascular disease risk: A two‐step Mendelian randomization study

Sleep Research, Volume 3, Issue 2, Page 108-120, June 2026.
The causal roles of metabolic traits in mediating the effects of insomnia on CVDs. CAD, coronary artery disease; HbA1c, hemoglobin A1c; HDL‐C, high‐density lipoprotein cholesterol; IR, insulin resistance; MI, myocardial infarction; TG, triglyceride; T2DM, type 2 diabetes.
Binhe Yu, Yanmin Xu, Xiaoyu Wang, Shuo Ye, Ruixiang Cui, Yujing Sun, Meng Li, Yan Li, Wenhui Yuan, Sheng Guo, Zhigang Chen, Xiaohong Kang, Sizhi Ai   +12 more
wiley   +1 more source

Two-Dimensional Dynamic Logic Resource Allocation for Scalable RIS Channel Emulation. [PDF]

Sensors (Basel)
Fei D, Zhang H, Chen C, Zhou H, Zheng P, Wang G, Li C, Zhang J, Song Z, Ai B.   +9 more
europepmc   +1 more source

Perspectives On Machine Learning Inference Serving in Real‐World Settings

Software: Practice and Experience, Volume 56, Issue 6, Page 734-757, June 2026.
ABSTRACT Introduction As machine learning (ML)‐enabled systems become increasingly prevalent across industries, the engineering challenges of deploying and maintaining them in production have emerged as critical. The existing engineering knowledge base often derives from conceptual frameworks or case studies conducted by large technology companies ...
Dennis Muiruri, Lucy Ellen Lwakatare, Jukka K. Nurminen, Tommi Mikkonen   +3 more
wiley   +1 more source

Performance and energy consumption optimization of ternary optical computers based on the M/G/1 queuing model. [PDF]

Sci Rep
Wenqiang S, Weiwen L, Heqiang Z, Meng L, Sulan Z, Xianchao W.   +5 more
europepmc   +1 more source