Results 161 to 170 of about 210,687 (314)

Targeting Lactate‐Driven Stromal Autophagy via MCT1 Disrupts the Immunosuppressive Niche and Sensitizes Pancreatic Cancer to PD‐1 Blockade

open access: yesAdvanced Science, EarlyView.
Tumor‐derived lactate activates PSCs through MCT1‐mediated Vps34 lactylation and autophagy. These activated PSCs secrete CXCL9/10, upregulating PD‐1 on CD8+ T cells via the CXCR3/STAT3 axis to foster immunosuppression. Disrupting this metabolic crosstalk by targeting MCT1 effectively sensitizes pancreatic cancer to PD‐1 blockade, presenting a promising
Wenfeng Zhuo   +14 more
wiley   +1 more source

Quiet!

open access: yes, 1946
Photograph used for a story in the Daily Oklahoman newspaper. Caption: "This is one battlefield where absolute quiet must reign. Dr. Bela Rozsa, left, Dr. Kester Svendsen, center, and A.H. Roddy.
McLaughlin, Al
core  

Quiet Trauma and the War in Ukraine

open access: yes
The photographic archive assembled by the students and academics at the Lviv Center for Urban History sits apart from familiar tropes of photojournalism.
Larsson, Chari
core   +1 more source

One‐Step Preparation of Lanthanide‐Doped Polyurea Multicolor Microspheres for Versatile Fluorescent Applications

open access: yesAdvanced Science, EarlyView.
Lanthanide‐doped polyurea microspheres are prepared via a facile one‐step precipitation polymerization. They exhibit strong hydrogen‐bonding and coordination interactions with excellent properties, including multicolor emission, high quantum yield (75.3%), remarkable stability, redispersibility, and biocompatibility.
Guiyu Zhang   +9 more
wiley   +1 more source

Are Quiet Periods Quiet? Evidence from Pre-earnings Announcement Quiet Periods

open access: yes
A growing number of companies have voluntarily developed and disclosed pre-earnings announcement quiet period policies. During quiet periods, companies restrict private communications with the investment community to prevent the selective disclosure of ...
Choy, So Yeoun
core  

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