Results 1 to 8 of about 8 (8)
Phase I/II study of adding intraperitoneal paclitaxel in patients with pancreatic cancer and peritoneal metastasis
BJS (British Journal of Surgery), Volume 107, Issue 13, Page 1811-1817, December 2020., 2020 This multicentre phase I/II study was undertaken to determine the recommended dose of the combination of intravenous gemcitabine, intravenous nab‐paclitaxel and intraperitoneal paclitaxel in patients with pancreatic ductal adenocarcinoma and peritoneal metastasis, and to evaluate its clinical efficacy and safety.S. Yamada, T. Fujii, T. Yamamoto, H. Takami, I. Yoshioka, S. Yamaki, F. Sonohara, K. Shibuya, F. Motoi, S. Hirano, Y. Murakami, H. Inoue, M. Hayashi, K. Murotani, J. Kitayama, H. Ishikawa, Y. Kodera, M. Sekimoto, S. Satoi +18 morewiley +1 more sourceAdjuvant therapy following oesophagectomy for adenocarcinoma in patients with a positive resection margin
BJS (British Journal of Surgery), Volume 107, Issue 13, Page 1801-1810, December 2020., 2020 In UK practice, surgical resection margin status is often used to stratify patients for receipt of adjuvant treatment. This cohort study suggested both an overall and recurrence‐free survival benefit following adjuvant therapy in patients with positive margins, who had undergone neoadjuvant chemotherapy and resectional surgery for oesophageal ...R. K. Bott, K. Beckmann, J. Zylstra, M. J. Wilkinson, W. R. C. Knight, C. R. Baker, M. Kelly, N. Maisey, A. Qureshi, T. Sevitt, M. Van Hemelrijck, E. C. Smyth, W. H. Allum, J. Lagergren, J. A. Gossage, D. Cunningham, A. R. Davies, Guy's and St Thomas' Oesophagogastric Research Group, R. McEwan, A. Jacques, N. Griffin, V. Goh, S. Ngan, K. Owczarczyk, H. Deere, M. Green, F. Chang, U. Mahadeva, B. Gill‐Barman, S. George, J. Meenan, M. Hill, J. Waters, M. Cominos, O. Hynes, A. Coombes, G. Tham, C. Iezzi, A. Reyhani, J. M. Dunn, S. S. Zeki +40 morewiley +1 more sourceComparison of the Peritoneal Cancer Index and Dutch region count as tools to stage patients with peritoneal metastases of colorectal cancer
BJS Open, Volume 4, Issue 6, Page 1153-1161, December 2020., 2020 This retrospective study compared two classification tools, the Dutch region count and the Peritoneal Cancer Index, for colorectal peritoneal metastases, and validated the results in a separate cohort. The region count was easier to apply, and may benefit doctors who refer patients to expert centres.F. S. Verheij, C. Bakkers, W. J. van Eden, A. G. J. Aalbers, S. W. Nienhuijs, K. Jóźwiak, I. H. J. T. de Hingh, N. F. M. Kok +7 morewiley +1 more sourceTumour growth rate of carcinoma of the colon and rectum: retrospective cohort study
BJS Open, Volume 4, Issue 6, Page 1200-1207, December 2020., 2020 Few studies have evaluated the growth pattern of colorectal cancer. Forty‐three patients who underwent CT twice more than 5 weeks apart were included over a 2‐year interval. The median doubling time was 211 days, with a concerning suggestion of tumour progression.J. R. Burke, P. Brown, A. Quyn, H. Lambie, D. Tolan, P. Sagar +5 morewiley +1 more sourceUpdate of the list of qualified presumption of safety (QPS) recommended microbiological agents intentionally added to food or feed as notified to EFSA 23: Suitability of taxonomic units notified to EFSA until September 2025
EFSA Journal, Volume 24, Issue 1, January 2026.Abstract
The qualified presumption of safety (QPS) process was developed to provide a harmonised safety assessment approach to support EFSA Scientific Panels and Units. The QPS approach assesses the taxonomic identity, body of relevant knowledge and safety of microorganisms intentionally added to the food and feed chain.EFSA Panel on Biological Hazards (BIOHAZ), Ana Allende, Avelino Alvarez‐Ordóñez, Valeria Bortolaia, Sara Bover‐Cid, Alessandra De Cesare, Wietske Dohmen, Laurent Guillier, Liesbeth Jacxsens, Maarten Nauta, Lapo Mughini‐Gras, Jakob Ottoson, Luisa Peixe, Fernando Perez‐Rodriguez, Panagiotis Skandamis, Elisabetta Suffredini, Marianne Chemaly, Pier Sandro Cocconcelli, Pablo Salvador Fernández Escámez, Miguel Prieto Maradona, Amparo Querol, Lolke Sijtsma, Juan Evaristo Suarez, Ingvar Sundh, Fulvio Barizzone, Justine Dastouet, Nadya Doyle, Sandra Correia, Lieve Herman +28 morewiley +1 more sourceUpdate of the list of qualified presumption of safety (QPS) recommended microbiological agents intentionally added to food or feed as notified to EFSA 22: Suitability of taxonomic units notified to EFSA until March 2025
EFSA Journal, Volume 23, Issue 7, July 2025.Abstract
The qualified presumption of safety (QPS) process was developed to assess the safety of microorganisms used in food and feed chains. During the period covered by this Statement, no new information warranted changes to the status of previously recommended QPS taxonomic units.EFSA Panel on Biological Hazards (BIOHAZ), Ana Allende, Avelino Alvarez‐Ordóñez, Valeria Bortolaia, Sara Bover‐Cid, Alessandra De Cesare, Wietske Dohmen, Laurent Guillier, Liesbeth Jacxsens, Maarten Nauta, Lapo Mughini‐Gras, Jakob Ottoson, Luisa Peixe, Fernando Perez‐Rodriguez, Panagiotis Skandamis, Elisabetta Suffredini, Pier Sandro Cocconcelli, Pablo Salvador Fernández Escámez, Miguel Prieto Maradona, Amparo Querol, Lolke Sijtsma, Juan Evaristo Suarez, Marianne Chemaly, Ingvar Sundh, Fulvio Barizzone, Justine Dastouet, Nadya Doyle, Sandra Correia, Lieve Herman +28 morewiley +1 more sourceThymopoietin‐α, ‐β, and ‐γ Isoforms Increased Expression in Cervical Cancer Cells
Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2025, Issue 1, 2025.Cervical cancer (CC) is a public health concern related to the human papillomavirus (HPV) persistent infection. Minichromosome maintenance 2 (MCM2) has been postulated as a surrogate marker for HPV infection. Thymopoietin (TMPO) is a nuclear protein regulated by E2F such as MCM2 or p16. TMPO can give rise to six different isoforms.Víctor Huerta-Padilla, Daniel Marrero-Rodríguez, Keiko Taniguchi-Ponciano, Ariana E. López, Fernando Candanedo-González, Emmanuel Salcedo, Alejandra Valdivia-Flores, Miriam Rodriguez-Esquivel, Laura Gómez Virgilio, Ricardo López-Romero, Maria de Jesus Nambo-Lucio, Sergio E. Meza-Toledo, Cindy Bandala, Marco A. Meraz, Mauricio Salcedo, Maria Lina Tornesello +15 morewiley +1 more source