Results 211 to 220 of about 31,201 (252)
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The American Journal of Medicine, 2009
One of the earliest antiarrhythmic drugs developed, quinidine had a significant role in the treatment of many arrhythmias. After concerns for increased risk of ventricular arrhythmia and death with quinidine emerged, the use of quinidine fell dramatically in favor of newer antiarrhythmic medications.
Felix, Yang +3 more
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One of the earliest antiarrhythmic drugs developed, quinidine had a significant role in the treatment of many arrhythmias. After concerns for increased risk of ventricular arrhythmia and death with quinidine emerged, the use of quinidine fell dramatically in favor of newer antiarrhythmic medications.
Felix, Yang +3 more
openaire +2 more sources
Quinidine-Digoxin Interaction [PDF]
New England Journal of Medicine, 1980 Abstract Administration of quinidine with digoxin increased serum digoxin concentrations in 79 patients and five volunteers. In 38 patients on a constant glycoside maintenance dose, the addition of quinidine to digoxin therapy resulted in a mean 2.5-fold increase (from 0.98±0.37 to 2.47±0.71 ng per milliliter, mean ±1 S.D ...
Graves P +5 more
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The Role of Quinidine in the Pharmacological Therapy of Ventricular Arrhythmias ‘Quinidine'
Mini-Reviews in Medicinal Chemistry, 2018Historically, quinidine was the first medicine used in the therapy of heart arrhythmias. Studies in the early 20th century identified quinidine, a diastereomer of the antimalarial quinine, as the most potent of the antiarrhythmic substances extracted from the cinchona plant.
Božić, Bojana +3 more
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2010
The cinchona alkaloid quinine and its d-diastereomer quinidine have been used for over 350 years for the treatment of malaria (Rocco, 2003). Although the bark of the cinchona tree had been used as a traditional medicine for the relief of fever by Andean healers, it was first used in Europe for ague (malaria) in the 17th century by Cardinal Juan de Lugo,
Hajkowicz, Krispin M., Cheng, Allen C.
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The cinchona alkaloid quinine and its d-diastereomer quinidine have been used for over 350 years for the treatment of malaria (Rocco, 2003). Although the bark of the cinchona tree had been used as a traditional medicine for the relief of fever by Andean healers, it was first used in Europe for ague (malaria) in the 17th century by Cardinal Juan de Lugo,
Hajkowicz, Krispin M., Cheng, Allen C.
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Rifampicin-quinidine interaction
British Journal of Diseases of the Chest, 1979Abstract Many interactions have been described between rifampicin and other drugs. They include increased metabolism of warfarin, glucocorticoids and oral contraceptives, presumably by enzyme induction (Zilly et al. 1977). We report the first documented case of an interaction between rifampicin and quinidine.
Praveen Mathur +4 more
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Quinidine, “pure quinidine,” and hydroquinidine
American Heart Journal, 1942Abstract 1. 1. Quinidine is composed of about 20 per cent hydroquinidine and 80 per cent “pure quinidine.” 2. 2. “Pure quinidine” is a marked cardiovascular depressant. It is much more toxic than quinidine in doses equivalent to sublethal doses of quinidine. 3. 3.
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The quinidine-digoxin interaction
International Journal of Cardiology, 1981In 1978, three groups independently described a drug interaction between quinidine and digoxin: When quinidine is given to patients taking digoxin, the serum digoxin concentration increases.1 2 3 T...
J. Thomas Bigger, J. Thomas Bigger
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JAMA: The Journal of the American Medical Association, 1979
To the Editor.— We wish to comment on the correspondence regarding the article "Interaction Between Quinidine and Digoxin" by Leahey et al (240:533, 1978) and the subsequent letters by Matzke and Burke (241:881, 1979) and Robert M. Cisneros, MS (241:881, 1979).
Louis P. Jeffrey, Darryl S. Rich
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To the Editor.— We wish to comment on the correspondence regarding the article "Interaction Between Quinidine and Digoxin" by Leahey et al (240:533, 1978) and the subsequent letters by Matzke and Burke (241:881, 1979) and Robert M. Cisneros, MS (241:881, 1979).
Louis P. Jeffrey, Darryl S. Rich
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Archives of Internal Medicine, 1983
Occasional patients, during administration of quinidine (usually for atrial tachyarrhythmias), begin to experience episodes of syncope. It has been estimated that this may occur in as many as 1% to 8% of patients receiving quinidine therapy. The usual mechanism of this quinidine-induced syncope has been shown to be a rapid, polymorphic ventricular ...
Sung Soon Kim, Steven Swiryn
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Occasional patients, during administration of quinidine (usually for atrial tachyarrhythmias), begin to experience episodes of syncope. It has been estimated that this may occur in as many as 1% to 8% of patients receiving quinidine therapy. The usual mechanism of this quinidine-induced syncope has been shown to be a rapid, polymorphic ventricular ...
Sung Soon Kim, Steven Swiryn
openaire +3 more sources