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Stereospecific Resistance to N2-Acyl Tetrahydro-β-carboline Antimalarials Is Mediated by a PfMDR1 Mutation That Confers Collateral Drug Sensitivity. [PDF]

open access: yesACS Infect Dis
Bremers EK   +9 more
europepmc   +1 more source

Efficacy and Safety of Antimalarial as Repurposing Drug for COVID-19 Following Retraction of Chloroquine and Hydroxychloroquine. [PDF]

open access: yesClin Pharmacol
Latarissa IR   +6 more
europepmc   +1 more source
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Quinine and Quinine Analogues

1984
Quinine, the oldest universally known antimalarial agent, has been the subject of numerous reviews in the past. We do not intend in this chapter to repeat once more all the known facts about quinine, but rather to select and critically discuss those properties which are essential for an assessment of its merits and its defaults in comparison with its ...
B. Merkli, W. Hofheinz
openaire   +2 more sources

Metabolism of quinine

Naunyn-Schmiedebergs Archiv f�r Experimentelle Pathologie und Pharmakologie, 1948
Studies of the comparative pharmacology of quinine revealed that rabbits possessed an unusual ability to metabolize this drug. The metabolic derivative formed by rabbit liver in vitro was isolated in pure crystalline form and found to possess a lower toxicity and antimalarial activity than quinine.
F. E. Kelsey, E. M. K. Geiling
openaire   +3 more sources

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