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The quinine connection

Journal of Antimicrobial Chemotherapy, 1992
Quinine, an alkaloid derived from the bark of the cinchona tree was brought to Europe from Peru in the 17th century. Isolation of quinine and other cinchona alkaloids was achieved in France in the early part of the 19th century and uncertainties of supply of the bark stimulated efforts to synthesize quinine.
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Quinine and Quinidine

2010
The cinchona alkaloid quinine and its d-diastereomer quinidine have been used for over 350 years for the treatment of malaria (Rocco, 2003). Although the bark of the cinchona tree had been used as a traditional medicine for the relief of fever by Andean healers, it was first used in Europe for ague (malaria) in the 17th century by Cardinal Juan de Lugo,
Hajkowicz, Krispin M., Cheng, Allen C.
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CUTANEOUS REACTION TO QUININ IN QUININ IDIOSYNCRASY

Journal of the American Medical Association, 1919
Some individuals are susceptible to the action of certain foreign substances. The urticarial rashes brought on by strawberries, the eczematoid dermatoses due to various proteins or food products, the asthma caused by white of egg, the hay-fever or asthma caused by pollens of plants or by inhalations of animal emanations or derivatives, the skin ...
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Quinine fever

Nature Chemistry, 2022
John G, Woodland, Kelly, Chibale
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The Quest for Quinine: Those Who Won the Battles and Those Who Won the War

Angewandte Chemie - International Edition, 2005
Teodoro S Kaufman
exaly  

C−H Activation Enables a Concise Total Synthesis of Quinine and Analogues with Enhanced Antimalarial Activity

Angewandte Chemie - International Edition, 2018
Daniel H O' Donovan   +2 more
exaly  

The Woodward–Doering/Rabe–Kindler Total Synthesis of Quinine: Setting the Record Straight

Angewandte Chemie - International Edition, 2007
Jeffrey I Seeman
exaly  

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