Results 21 to 30 of about 371 (108)

Evidence for early endothelial dysfunction associated with the ALDH2 rs671 gene variant: A preliminary investigation with young East Asians

Experimental Physiology, EarlyView.
Abstract Aldehyde dehydrogenase 2 (ALDH2) is a mitochondrial enzyme that plays an important role in aldehyde detoxification. A large percentage (30–50%) of the East Asian population carry a single point mutation in the ALDH2 gene (ALDH2*2 variant) that causes a severe reduction or lack of ALDH2 enzyme activity, and leads to disrupted cellular ...
Beatrice Lioy, Wagner Ribeiro Pereira, Rehan Junejo, Tiago Peçanha, Guilherme Giannini Artioli   +4 more
wiley   +1 more source

Similarities and differences in carotid artery, hemodynamic, and autonomic reactivity induced by mental stress or cold in adults: A randomized crossover study

Physiological Reports, Volume 14, Issue 5, March 2026.
The Stroop test and cold pressor test elicit comparable common carotid artery vasodilation. However, mental stress induced by the Stroop test leads to an earlier peak response, possibly influenced by anticipatory mechanisms. Created in BioRender. Speretta, G. (2026) https://BioRender.com/mwpc1hw.
Francisco J. Fensterseifer, Iara G. Teixeira, Welliton Oracz, Richard E. Filipini, Francine Stein, Guilherme F. Speretta   +5 more
wiley   +1 more source

Peripheral chemoreflex restrains skeletal muscle blood flow during exercise in participants with treated hypertension

The Journal of Physiology, Volume 603, Issue 18, Page 5091-5102, September 15, 2025.
Abstract figure legend Cardiorespiratory and brachial artery haemodynamic assessments were made during intravenous infusion of low‐dose dopamine, to inhibit the peripheral chemoreflex, and saline (control) at rest, and during hypoxia and rhythmic handgrip exercise in people with hypertension.
Ana Luiza C. Sayegh, Michael J. Plunkett, Thalia Babbage, Mathew Dawes, Julian F.R. Paton, James P. Fisher   +5 more
wiley   +1 more source

Adverse Cardiovascular Risk Profile and Increased Diurnal Salivary Cortisol in Girls With Turner Syndrome: An Exploratory Study

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, Volume 199, Issue 2, Page 116-123, June 2025.
ABSTRACT Patients with Turner Syndrome (TS) and those exposed to high concentrations of glucocorticoids have a number of characteristics in common, including an increased risk of cardiovascular disease. Pediatric TS patients underwent studies of salivary cortisol (SC) and cortisone (SCn), body composition, continuous glucose monitoring, vascular ...
Lily Jones, Julie Park, Silothabo Dliso, Daniel B. Hawcutt, Alena Shantsila, Gregory Y. H. Lip, Joanne Blair   +6 more
wiley   +1 more source

The U.S. POINTER neurovascular ancillary study: Study design and methods

Alzheimer's &Dementia, Volume 21, Issue 2, February 2025.
Abstract INTRODUCTION POINTER Neurovascular (POINTER‐NV) is an ancillary study that leverages the rich infrastructure and design of the U.S. Study to Protect Brain Health through Lifestyle Intervention to Reduce Risk (U.S. POINTER) to investigate neurovascular mechanisms that may underlie intervention effects on key brain outcomes.
Tina E. Brinkley, Katelyn R. Garcia, Gary F. Mitchell, Charles H. Tegeler, Aarti Sarwal, John Bennett, Dalane W. Kitzman, Iris Leng, Laura D. Baker, Mark A. Espeland, Heather M. Snyder, Jurgen A. Claassen, Margie J. Bailey, Hossam A. Shaltout   +13 more
wiley   +1 more source

Higher amounts of habitual physical activity changes the relationship between hot flashes and subclinical cardiovascular disease risk

Physiological Reports, Volume 13, Issue 3, February 2025.
Abstract The menopausal transition is associated with increased risk for cardiovascular disease (CVD). Hot flashes (HF), a cardinal symptom of menopause, have been associated with increased CVD risk, particularly in perimenopausal women. Flow‐mediated dilation (FMD) is an indicator of endothelial function and a subclinical CVD risk factor.
Sarah Witkowski, Tint Tha Ra Wun, JoSophia Brunzelle, Sara Buszkiewicz, Lorna Murphy, Randi L. Garcia, Lynnette Leidy Sievert   +6 more
wiley   +1 more source

Impact of moderate‐intensity aerobic exercise in combined hypoxic and hot conditions on endothelial function

Clinical Physiology and Functional Imaging, Volume 44, Issue 6, Page 415-425, November 2024.
Abstract There is no study that has investigated the impact of exercise in a combined hypoxic and hot environment on endothelial function. Therefore, we tested whether aerobic exercise in a combined hypoxic and hot conditions induces further enhancement of endothelial function.
Takuma Morishima, Keiichi Yamaguchi, Kazushige Goto   +2 more
wiley   +1 more source

Acute impact of inorganic nitrate supplementation after ischemia and during small muscle mass exercise in postmenopausal females: A pilot study

Physiological Reports, Volume 12, Issue 19, October 2024.
Abstract Menopause is associated with reduced endothelial‐dependent vasodilation and increased cardiovascular disease (CVD) risk. Dietary nitrate, a non‐pharmacological approach, may increase vasodilatory capacity consequentially reducing CVD risk. We investigated macro‐ and microvascular function after acute nitrate supplementation in postmenopausal ...
Jacob T. Caldwell, Alyssa Koenke, Lauren Zimmerman, Aaron E. Wahl, Sarah A. Fenn, Emily E. Grammer, Macy E. Stahl, Jason D. Allen, Salvador J. Jaime   +8 more
wiley   +1 more source

Software medical device maintenance: DevOps based approach for problem and modification management

Journal of Software: Evolution and Process, Volume 36, Issue 4, April 2024.
Software problem resolution and change control processes are crucial for the performance, safety, and regulatory clearance of a medical device. Software changes are frequent throughout the whole life cycle of a product; therefore, iterative analysis and risk assessment are necessary to determine the impact of changes on the whole system.
Maria Raffaella Martina, Elisabetta Bianchini, Sara Sinceri, Martina Francesconi, Vincenzo Gemignani   +4 more
wiley   +1 more source

Relationship between measures of adiposity, blood pressure and arterial stiffness in adolescents. The MACISTE study. [PDF]

J Hypertens, 2023
Pucci G, Martina MR, Bianchini E, D'abbondanza M, Curcio R, Battista F, Anastasio F, Crapa ME, Sanesi L, Gemignani V, Vaudo G.   +10 more
europepmc   +1 more source