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Quorum Quenching

2021
Bakterien sind in der Lage, ihre Artgenossen in der Umgebung über unterschiedliche Signalmoleküle wahrzunehmen und über bestimmte Signalwege auf steigendes Zellwachstum gemeinschaftlich zu reagieren. Bezeichnet wird dieser Vorgang als Quorum Sensing und stellt ein Art bakterielle Sprache dar. Bei pathogenen Organismen führt diese Kommunikation meist zu
Vollstedt, Christel, Streit, Wolfgang
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Trends in Quorum Sensing and Quorum Quenching

2023
Quorum sensing (QS), controls the characteristics of microbe populations through the detection of the concentrations of signal molecules, which are not only released but also produced by bacteria. QS regulates both biochemical and physiological functions viz., release of quorum signal molecules, biofilm formation, reduction in virulence, production of ...
Ashwitha Kodaparthi   +1 more
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Towards quorum-quenching catalytic antibodies

Chem. Commun., 2009
The development of a novel method to attenuate bacterial virulence is reported, which is based upon the use of designed transition-state analogues to select human catalytic antibodies capable of degrading bacterial quorum-sensing molecules.
Prashant B, Kapadnis   +5 more
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Quorum Sensing and Quorum Quenching in Food-Related Bacteria

2020
Fil: Tomadoni, Barbara Maria. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnologia de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingenieria.
Tomadoni, Bárbara María   +1 more
openaire   +2 more sources

Quo vadis quorum quenching?

Current Opinion in Pharmacology, 2013
With the emergence of microbial pathogens increasingly resistant against commonly used antibiotics, new treatment strategies are desperately needed. Bacterial quorum sensing has attracted a lot of attention over the last decade as a potential new target for antimicrobial therapy.
Jie, Zhu, Gunnar F, Kaufmann
openaire   +2 more sources

Quorum quenching enzymes

Journal of Biotechnology, 2015
Bacteria use cell-to-cell communication systems based on chemical signal molecules to coordinate their behavior within the population. These quorum sensing systems are potential targets for antivirulence therapies, because many bacterial pathogens control the expression of virulence factors via quorum sensing networks.
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Quorum Quenching

2023
Antibiotic resistance is a global health concern. Strains of pathogenic microorganisms that have developed resistance to multiple antibiotics, such as MRSA, are extremely difficult to treat, and alternative methods for tackling pathogenic microorganisms are in demand.
openaire   +1 more source

Biotechnological applications of quorum quenching enzymes

Chemico-Biological Interactions, 2017
Numerous bacteria use quorum sensing (QS) to synchronize their behavior and monitor their population density. They use signaling molecules known as autoinducers (AI's) that are synthesized and secreted into their local environment to regulate QS-dependent gene expression. Among QS-regulated pathways, biofilm formation and virulence factor secretion are
Bzdrenga, Janek   +6 more
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Quorum‐sensing quenching by rhizobacterial volatiles

Environmental Microbiology Reports, 2011
Summary We show that volatile organic compounds (VOCs) produced by rhizospheric strains Pseudomonas fluorescens B‐4117 and Serratia plymuthica IC1270 may act as inhibitors of the cell–cell communication quorum‐sensing (QS) network ...
Leonid, Chernin   +6 more
openaire   +2 more sources

Disrupting the bacterial language: quorum quenching and its applications

Critical reviews in microbiology
Quorum sensing (QS) is a bacterial communication method closely linked with population density and regulates biofilm formation and the secretion of virulence factors through the release, recognition, and prompt response to small molecule signals.
Yeting Tu   +8 more
semanticscholar   +1 more source

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