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Generation of Quorum Quenching Antibodies
2010The exchange of information within and among bacterial populations using small diffusible molecules has been termed "quorum sensing" (QS). Due to the extracellular distribution of the QS autoinducer molecules and the evolutionary highly conserved nature of signaling components, microbial QS systems represent an excellent target for anti-infective ...
Gunnar F, Kaufmann +4 more
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Quorum Quenching for Sustainable Environment
2021Quorum quenching is the process that prevents quorum sensing through the disruption of signalling cascade and bacterial communication among themselves mediated by the degradation of the signalling molecules. Therefore, quorum quenching has a considerable contribution in the negative regulation of threatening diseases and eventually increasing soil ...
Sumira Malik +6 more
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Quorum quenching and proactive host defense
Trends in Plant Science, 2003Both plants and humans have inducible defense mechanisms. This passive defense strategy leaves the host unprotected for a period of time until resistance is activated. Moreover, many bacterial pathogens have evolved cell-cell communication (quorum-sensing) mechanisms to mount population-density-dependent attacks to overwhelm the host's defense ...
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Quorum sensing and quorum-quenching enzymes.
Journal of microbiology (Seoul, Korea), 2005To gain maximal benefit in a competitive environment, single-celled bacteria have adopted a community genetic regulatory mechanism, known as quorum sensing (QS). Many bacteria use QS signaling systems to synchronize target gene expression and coordinate biological activities among a local population.
Yi-Hu, Dong, Lian-Hui, Zhang
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Quorum Sensing and Quorum Quenching Facebook of Microbial World
International Journal of Scientific Research, 2012Dental Plaque is an example of biofilm leading to periodontal disease and dental caries. Many Gram-positive and Gram-negative bacteria communicate using small diffusible signal molecules called autoinducers. This process, known as quorum sensing, links cell density to the expression of genes as diverse as those associated with virulence fac- tors ...
Dr. Babita Sahu +5 more
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Quorum Sensing and Quorum Quenching in Soil Ecosystems
2010Several bacteria originating from soil ecosystems have evolved the ability to regulate gene expression as a function of their cell density, a phenomenon called quorum sensing (QS). To do so bacteria communicate via the production and sensing of signal molecules. The most common class of signals clusters N-acyl homoserine lactones (AHL) molecules.
Yves Dessaux +2 more
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Quorum Quenching: Impact and Mechanisms
2014This chapter focuses on the impact and molecular mechanisms of quorum quenching, with emphasis on quorum-quenching enzymes and other signal disruption mechanisms. There are five key processes in quorum-sensing circuit, (i) signal generation, (ii) signal transportation, (iii) signal accumulation, (iv) signal recognition, and (v) signal autoinduction ...
Lian-Hui Wang +2 more
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Biofouling Control by Quorum Quenching
2015Bacteria above a threshold cell density regulate the expression of a specific group of their genes in response to small signal molecules called autoinducers. This twitter communication phenomenon is called quorum sensing (QS). Among the various genetic expressions mediated by QS , biofilm formation and expression of virulence factors are the most ...
Vipin C. Kalia +3 more
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Signal Molecule-Dependent Quorum-Sensing and Quorum-Quenching Enzymes in Bacteria
Critical Reviews in Eukaryotic Gene Expression, 2014The quick spread of nosocomial bacterial infections and the increasing prevalence of drugresistant strains make the development of novel drugs for pathogens an urgent priority. Quorum sensing (QS) is a communication mechanism used by bacteria to recognize population density fluctuations and control gene expression, which play a critical role both in ...
Yanfen, Du +4 more
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Exploring alternative quorum sensing model structures and quorum quenching strategies
2023AbstractBacterial quorum sensing (QS) is a cell-to-cell communication mechanism through which bacteria share information about cell density, and tune gene expression accordingly. Pathogens exploit QS to orchestrate virulence and regulate the expression of genes related to antimicrobial resistance.
Chiara Cimolato +5 more
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