Results 111 to 120 of about 52,992 (283)
Forme e tipologie dell’autocitazione negli scritti di Epicuro [PDF]
Parole Rubate, 2019 This article offers a classification of various forms and types of intratextuality in Epicurus’ work. Starting from the main distinction between external and internal references to/within a text, this analysis focuses on didactic and argumentative ...
Vincenzo Damiani
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The position of Rudaki in the verses of Amir Moezi and other poets [PDF]
متن شناسی ادب فارسی, 2009 Rudaki is the first great poet in the Persian Literature. He is known to compose so many poems. He is also considered to be one of the earliest poets among Persian poets.
A.R Yalameha
doaj
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Using Quotation Marks Correctly
, 2011 Our use of quotation marks should be consistent and take into account reader expectations. We write for American readers, educated in the American style, so we should follow the American rules when using quotation marks.
Fordyce-Ruff, Tenielle
core
“Utinam ne in nemore Pelio”. Un verso di Ennio nelle opere di Cicerone [PDF]
Parole Rubate, 2019 Rapidly become a literary topos, Ennius’s line utinam ne in nemore Pelio refers to certain events one wished had not unfolded, given the far-reaching consequences they had. In his works, Cicero quotes Ennius’s line repeatedly.
Alessandra Di Meglio
doaj
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source