Results 151 to 160 of about 52,992 (283)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Parents' and guardians' perceptions of sexual and reproductive health communication with youth: A qualitative study in Gurage Zone, Southern Ethiopia. [PDF]

PLOS Glob Public Health
Nida GG, Khunou SH, Mphuthi D.
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

A Theory of Planned Behaviour Analysis of Barriers and Facilitators of Immediate Postpartum Contraception Uptake in Southwestern Uganda. [PDF]

Open Access J Contracept
Ainomugisha B, Owaraganise A, Tumuhimibise W, Naiga P, Asiimwe J, Kamugisha A, Bwengye M, Alinda N, Kayondo M, Ngonzi J.   +9 more
europepmc   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Fear of Being Judged: A Phenomenological Hermeneutical Study of Encountering Ambulance Staff When Living in Stigmatized Neighbourhoods. [PDF]

Scand J Caring Sci
Björklund S, Hagell P, Hagell PL, Holmberg M.   +3 more
europepmc   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Everyday social contexts influence fluctuations into and out of chronic pain: an ethnographic study in England. [PDF]

BMJ Open
Stone S, Zeyen A, Gooberman-Hill R.
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

How Quotation Types Shape Classic Novel Reading in Chinese: A Comparison Between Human Eye-Movements and Large Language Models. [PDF]

Behav Sci (Basel)
Chen L, Zuo W, Xu X.
europepmc   +1 more source