Results 131 to 140 of about 202,247 (341)

Structural Basis of Regioselective Bromination of Tricyclic Tryptoline by the Tryptophan Halogenase Thal

open access: yesChemBioChem, EarlyView.
This study shows that the flavin‐dependent tryptophan halogenase Thal also regioselectively halogenates the tricyclic non‐native substrate tryptoline, a β‐carboline with various pharmacological activities. Interestingly, Thal brominates a different position of the shared pharmacophore indole in tryptoline than it does in tryptophan. A crystal structure
Simon Bork   +3 more
wiley   +1 more source

First‐order Sobolev spaces, self‐similar energies and energy measures on the Sierpiński carpet

open access: yesCommunications on Pure and Applied Mathematics, EarlyView.
Abstract For any p∈(1,∞)$p \in (1,\infty)$, we construct p$p$‐energies and the corresponding p$p$‐energy measures on the Sierpiński carpet. A salient feature of our Sobolev space is the self‐similarity of energy. An important motivation for the construction of self‐similar energy and energy measures is to determine whether or not the Ahlfors regular ...
Mathav Murugan, Ryosuke Shimizu
wiley   +1 more source

Respiratory quotient in obese subjects [PDF]

open access: green, 1932
D. M. Lyon   +2 more
openalex   +1 more source

Boundary conditions and universal finite‐size scaling for the hierarchical |φ|4$|\varphi |^4$ model in dimensions 4 and higher

open access: yesCommunications on Pure and Applied Mathematics, EarlyView.
Abstract We analyse and clarify the finite‐size scaling of the weakly‐coupled hierarchical n$n$‐component |φ|4$|\varphi |^4$ model for all integers n≥1$n \ge 1$ in all dimensions d≥4$d\ge 4$, for both free and periodic boundary conditions. For d>4$d>4$, we prove that for a volume of size Rd$R^{d}$ with periodic boundary conditions the infinite‐volume ...
Emmanuel Michta   +2 more
wiley   +1 more source

Taste Profile and Relative Bioavailability of Tovorafenib Powder for Oral Suspension and Food Effect of the Tovorafenib Tablet in Healthy Participants

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract A pediatric‐friendly powder for oral suspension (PfOS) of tovorafenib, a type II RAF inhibitor, was developed for patients with difficulty swallowing tablets. This open‐label, randomized, phase 1 study (QSC205140) evaluated the taste/palatability of PfOS formulations (n = 12), the relative bioavailability of the PfOS versus tablet formulation,
Yang Zhang   +6 more
wiley   +1 more source

Surface Deposition of Dome‐Shaped Metal‐Organic Complexes: A New Approach to the Generation of Single‐Site Catalysts

open access: yesChemPlusChem, EarlyView.
This study describes the synthesis of a new dithia‐[2.1.1]‐(2,6)‐pyridinophane ligand and its molybdenum(0) tricarbonyl complex. Monolayers of the dome‐shaped complex on Au(111) are investigated by employing surface spectroscopic methods (infrared reflection absorption spectroscopy, X‐ray photoelectron spectroscopy, near‐edge X‐ray absorption fine ...
Küpra Yildiz   +4 more
wiley   +1 more source

A Generalized Ring of Quotients II [PDF]

open access: bronze, 1958
George D. Findlay, J. Lambek
openalex   +1 more source

Tackling Environmental Impact: A New Support Tool for Sustainable Healthcare Waste Management

open access: yesCorporate Social Responsibility and Environmental Management, Volume 32, Issue 4, Page 4403-4419, July 2025.
ABSTRACT This study proposes a novel framework integrating Environmental Risk Assessment (ERA) and Material Flow Analysis (MFA) within the Deming Cycle framework to address this gap. While valuable tools, ERA and MFA offer limited perspectives on environmental impact when used alone.
Carlotta D'Alessandro   +4 more
wiley   +1 more source

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