Results 201 to 210 of about 8,764,171 (325)

The crystal structure of the RNA/DNA hybrid r(GAAGAGAAGC){middle dot}d(GCTTCTCTTC) shows significant differences to that found in solution [PDF]

, 1999
Graeme L. Conn, Tom Brown, Gordon A. Leonard   +2 more
openalex   +1 more source

International operations and corporate R&D investment: Evidence from China. [PDF]

PLoS One
Fu Y, Li J, Wu Y.
europepmc   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Syzygium schlechterianum: Hequet, V., Vandrot, H., Barrabé, L., Amice, R., Butin, J.-P., Cazé, H., Fleurot, D., Suprin, B., Chambrey, C., Laudereau, C., Haverkamp, C. & Fogliani, B.

, 2018
IUCN
openalex   +1 more source

A Framework for Considering the Role of the Public Sector in R&D of Health Technology. [PDF]

Pharmaceut Med
Rejon-Parrilla JC, Epstein D, Mestre-Ferrandiz J, Espin J.   +3 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Oxyagrion simile: Vilela, D. & Guillermo-Ferreira, R.

, 2019
IUCN
openalex   +1 more source

Strategic resilience: Exploring diversification's impact on R&D investment during economic crises. [PDF]

Heliyon
Nguyen TBC, Nguyen QN.
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Echymipera echinista: Leary, T., Wright, D., Hamilton, S., Singadan, R., Menzies, J., Bonaccorso, F., Helgen, K., Seri, L., Aplin, K., Dickman, C. & Salas, L.

, 2008
IUCN
openalex   +1 more source