Results 291 to 300 of about 8,764,171 (325)

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Retraction: Digital inclusive finance, R&D investment, and green technology innovation nexus. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Retraction: How does multidimensional R&D investment affect green innovation? Evidence from China. [PDF]

Front Psychol
Frontiers Editorial Office.
europepmc   +1 more source

Innovating under different competitive strategies: The impact of R&D on risk and return in dynamic environments. [PDF]

PLoS One
Morina D, Lucas H, Heiden S.
europepmc   +1 more source

Impact of National Centralized Drug Procurement policy on chemical pharmaceutical enterprises' R&D investment: a difference-in-differences analysis in China. [PDF]

Front Public Health
Li J, Zhang X, Wang R, Cao K, Wan L, Ren X, Ding J, Li W.   +7 more
europepmc   +1 more source

The complex impact of China's science and technology talent policies on key core technologies R&D. [PDF]

PLoS One
Miao P, Zhang X, Zhang N.
europepmc   +1 more source

Measurement of R(D) and R(D*) with a Semileptonic Tagging Method

, 2019
openaire   +1 more source

R&D Depreciation Rates in the 2007 R&D Satellite Account [PDF]

, 2007
This paper is part of a series that provides the details behind the Bureau of Economic Analysis’s (BEA) satellite account on research and development (R&D) activity. In the current work, the focus is on industry-specific depreciation rates for business R&D capital. This paper begins by discussing the literature on R&D depreciation rates.
Charles Ian Mead
openaire   +3 more sources

On the Failure of R&D Projects. [PDF]

IEEE Trans. Engineering Management, 2015
There is an extensive literature on the success/failure of firm-funded R&D projects but growing policy interest focuses on publicly-funded R&D projects. Using data from 1,878 Phase II R&D projects funded through the U.S. Small Business Innovation Research (SBIR) program, of which 624 had been discontinued prior to technical completion, we provide for ...
Link, AN, Wright, M
openaire   +2 more sources

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R(D) and R(D*) anomalies and their phenomenological implications

Nuclear and Particle Physics Proceedings, 2017
Recently, BaBar, Belle and LHCb have found hints of lepton flavour universality violation in B→D(⁎)τν‾τ decays, i.e., the measured ratios R(D(⁎))=B(B→D(⁎)τν‾τ)/B(B→D(⁎)lν‾l)(l=e/μ) show a combined 3.8 σ deviation from the SM predictions. In this talk, we will discuss two possible solutions to the observed R(D) and R(D*) anomalies: one with an EW-scale ...
openaire   +1 more source