Results 21 to 30 of about 354,996 (199)

Starspot Area Coverage: Correlation with Age and Spectral Type in FGK and M Stars

The Astrophysical Journal Letters
Starspots, analogous to sunspots, are surface manifestations of stellar magnetic activity. Their study provides crucial insights into stellar dynamo processes and the evolution of magnetic phenomena.
Alexandre Araújo, Ciria Lima, Fabian Menezes, Adriana Valio   +3 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Bimodality in Rotational Modulation of Planet-hosting Stars

The Astrophysical Journal Letters
Stellar magnetic activity is governed by the interplay between rotation, convection, and the temporal evolution of surface magnetic structures, yet the role of planetary systems in shaping these processes remains unclear.
Alexandre Araújo, Adriana Valio
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

A promoção da saúde pelas ondas do rádio: um foco na propaganda de medicamentos

Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia, 2014
Este trabalho refere-se à experiência desenvolvida em parceria com a Agência Nacional de Vigilância Sanitária, Vigilância Sanitária Municipal de Juiz de Fora − MG e Faculdade de Farmácia da Universidade Federal de Juiz de Fora, envolvendo radiocomunicadores, profissionais e acadêmicos da saúde para reflexão e discussão sobre o Uso ...
Alessandra Ésther Mendonça, Milene Evelyn da Silva, Carolina Pires Araújo, Bianca Roberta Campos, Allan de Gouvêa Pereira, Luiz Paulo Reis Santos, Miriam Aparecida de Oliveira Pinto, Thais de Sá Pecis, Vivian Henriques do Amaral, Lilian Henriques do Amaral, Simone Gatti Ferreira Reis, Mônica Cecília Santana Pereira, Maria da Penha Henriques do Amaral   +12 more
openaire   +2 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Differential Rotation of CoRoT Stars and a Kepler Binary Star from Starspot Transit Mapping

The Astrophysical Journal
While direct magnetic field measurements are rare for slowly rotating stars, spots observed during planetary transits provide a potential indicator of magnetic activity on stellar surfaces.
Adriana Valio, Alexandre Araújo, Fabian Menezes   +2 more
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Verbo fálico: sobre o erotismo divino na canção Sobre todas as coisas de Chico Buarque e Edu Lobo

Per Musi, 2014
Este artigo pretende realizar uma leitura interpretativa da canção Sobre todas as coisas, composta por Chico Buarque e Edu Lobo, gravada originalmente no LP O grande circo místico (1983).
Márcio Ronei Cravo Soares
doaj  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source