Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy
Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann +25 more
wiley +1 more source
PARIS Y SU REGIMEN ESPECIAL DE GOBIERNO Y ADMINISTRACION LOCAL.
Manuel Alarcón Martín
doaj +3 more sources
Impact of HIV disclosure and related predictors on CD4 cell count among adults under first-line ART regimen at Felege Hiwot comprehensive specialized referral hospital, North West Ethiopia. [PDF]
Bekele AA, Tegegne AS, Muhie NS.
europepmc +1 more source
Micro/Nanorobot for Drug Delivery—A Review of Material Selections
This review explores material strategies for biomedical micro/nanorobots, emphasizing their roles in propulsion, navigation, drug delivery, and biodegradability. It highlights advancements in metallic, polymeric, and hybrid materials, while addressing clinical translation challenges such as toxicity, immune response, and manufacturability.
Xiaozhuo Wu, Bingyun Li, Malcolm Xing
wiley +1 more source
Advances and Challenges in Micro/Nanocarrier‐Based Dermal Drug Delivery Systems for Acne Treatment
Topical acne treatment faces challenges from skin barriers and complex causes. Micro/nanocarriers improve drug delivery by enhancing bioavailability, targeting, and duration. Combining carriers creates synergistic effects for systematic intervention.
Jintao Yang +7 more
wiley +1 more source
EL SISTEMA ESPECIAL DE LONDRES DENTRO DEL REGIMEN LOCAL INGLES.
José Francisco Carreira Verez
doaj +3 more sources
Número especial. Neoliberalismo en Costa Rica: cuatro décadas de advertencias inadvertidas. Propuestas para encauzar el régimen político-económico institucional costarricense del siglo XXI.
Revista Espiga
doaj
Factores asociados al tratamiento no exitoso para tuberculosis en pacientes previamente tratados en Cali, Colombia, en el periodo 2015-2019] [PDF]
Salvatierra Hilares JC.
europepmc +1 more source
Antibacterial Applications of Black and Violet Phosphorus‐Based Biomaterials
Black and violet phosphorus‐based biomaterials exhibit broad‐spectrum antibacterial efficacy in various infections, including bone, skin, ocular, dental, lung, and sepsis cases. Their antibacterial mechanisms include physical disruption, light‐driven effects, targeted drug delivery, and enhanced composite strategies.
Zhuo Dai +8 more
wiley +1 more source
Real-World Experience of Weekly Carfilzomib in Combination with Cyclophosphamide and Dexamethasone in Multiple Myeloma Relapsed/Refractory to Bortezomib and Lenalidomide. [PDF]
Yang C +8 more
europepmc +1 more source

