Results 31 to 40 of about 669,721 (248)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Al-Qaida y la matanza de Bali [PDF]

open access: yes, 2002
El atentado perpetrado en Bali, Indonesia, el pasado 12 de octubre ha sido calificado como el peor desde los cometidos el 11 de septiembre y también uno de los que más víctimas ha causado en toda la historia del terrorismo en el mundo.
Avilés, Juan
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Prohibición de allanamiento y transacción sobre los bienes y derechos de las Corporaciones Locales

open access: yesRevista de Estudios de la Administración Local y Autonómica, 1983
SUMARIO: I. INTRODUCCIÓN. — II. ÁMBITO DE LOS BIENES Y DERECHOS QUE NO PUEDEN SER OBJETO DE TRANSACCIÓN O ALLANAMIENTO, SALVO CON AUTORIZACIÓN POR DECRETO DEL GOBIERNO. — III. PROCEDIMIENTO PARA LA TRANSACCIÓN O ALLANAMIENTO. — IV.
Fernando Rodrigo Moreno
doaj   +1 more source

El derecho al agua en la legislación española [PDF]

open access: yes, 2011
[Resumen] Este estudio contiene una reflexión sobre el significado actual del derecho al agua, que tiene en cuenta la evolución de la legislación española histórica y vigente, tanto la específica de aguas como la de régimen local, la sanitaria y la ...
Menéndez Rexach, Ángel
core   +1 more source

El marc local i la prestació dels serveis municipals a l'àrea MAB-6 ALT PIRINEU [PDF]

open access: yes, 1988
L'analyse détaillée, dans les municipalités de la zone MAB-6 HAUTES PYRENNÉES, des équipements municipaux, des prestations de services et de la législation applicable localement constitue la base de la réflexion sur la fonctionnalité et sur les ...
Mateu, Xavier
core   +3 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Desarrollo regional y reforma del régimen local

open access: yesRevista de Fomento Social, 1972
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Victorino Ortega
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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