Results 101 to 110 of about 5,017,645 (251)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
IMPACT OF STRUCTURAL FUNDS ON REGIONAL GROWTH: HOW TO RECONSIDER A 9 YEAR-OLD BLACK BOX [PDF]
Econometric estimations of the impact of structural funds on the growth process of the European regions started 9 years ago. However, it is striking to realize that all previous estimations in this field are based on some form of the neoclassical growth ...
Julie LE GALLO +2 more
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Front Matter Vol. 18 No.1 (2023)
Region: Jurnal Pembangunan Wilayah dan Perencanaan Partisipatif, 2023 Jurnal Region
doaj +1 more source
EMPIRICS OF THE METROPOLITAN PRODUCTIVITY PATTERNS IN EUROPE [PDF]
This paper focuses on the main European metropolitan areas and builds empirics on their evolution over the process of economic integration these last twenty years.
Christian LONGHI
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Back Matter Vol. 18 No.1 (2023)
Region: Jurnal Pembangunan Wilayah dan Perencanaan Partisipatif, 2023 Jurnal Region
doaj +1 more source
Bulletin de la Dialyse à DomicileCalciphylaxis is a rare and potentially fatal disease manifested by progressive skin ulcerations due to calcification and obstruction of small-caliber arteries and arterioles.
Pablo Antonio Ureña Torres +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source