Results 191 to 200 of about 5,017,645 (251)

Unburnable carbon in the rapidly warming Arctic: Mapping spatial relationships among oil and gas development, ecologically sensitive areas and Indigenous Peoples' lands. [PDF]

PLoS One
Codato D, Vezzelli D, Ammaturo F, Lazazzera G, Stralla A, Pappalardo SE, De Marchi M.   +6 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Front Matter Vol. 20 No.2 (2025)

Region: Jurnal Pembangunan Wilayah dan Perencanaan Partisipatif
Jurnal Region
doaj  

Development and external validation of a novel prediction model for the TraumaTriage App. [PDF]

Eur J Trauma Emerg Surg
Gulickx M, Lokerman RD, van der Sluijs R, Tuinema RM, van Vliet R, Hietbrink F, Groenwold RHH, van Heijl M.   +7 more
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Back Matter Vol. 20 No.2 (2025)

Region: Jurnal Pembangunan Wilayah dan Perencanaan Partisipatif
Jurnal Region
doaj  

Tumor cell-free DNA detection in CSF for primary CNS lymphoma diagnosis

Acta Neuropathologica Communications, 2019
V. Rimelen, G. Ahle, E. Pencreach, N. Zinniger, A. Debliquis, L. Zalmaï, I. Harzallah, R. Hurstel, I. Alamome, F. Lamy, J. Voirin, B. Drénou   +11 more
doaj   +1 more source

Minutes of the Annual Meeting [PDF]

, 2020

core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Burden of metabolic dysfunction-associated steatotic liver disease in the Asia-Pacific region from 1990 to 2023. [PDF]

eGastroenterology
Zhou XD, Chen QF, Targher G, D Byrne C, Valenti L, Muthiah MD, Kim SU, Huang DQ, Yoneda M, Li W, Yilmaz Y, Tilg H, Wong VW, Zheng MH.   +13 more
europepmc   +1 more source