Results 71 to 80 of about 5,017,645 (251)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
BelgeoCet opus de Belgeo revient sur l’analyse de la région en géographie et en aménagement du territoire, au regard des évolutions de régions existantes et des formes et modalités de régionalisation qui émergent à différentes échelles, plus ou moins ...
Thomas Perrin
doaj +1 more source
METROPOLITAN DEVELOPMENT AND COOPERATION IN SOUTH-EASTERN EUROPE [PDF]
This paper explores the role and importance of the four, closelocated, metropolises of south-eastern Europe (Skopje, Sofia, Thessaloniki and Tirana) and proposes a strategy that promotes metropolitan growth and development, maximizes spread effects to ...
George PETRAKOS, Paschalis ARVANITIDIS
core
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Altruistic bequests and non-negative savings [PDF]
This paper builds on the class of models studying the game interaction between an altruistic benefactor and a selfish recipient. An altruistic parent's bequest is transferred to his selfish son after the former's death and we assume that it is not a ...
Stéphane LAMBRECHT
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
EDUCATIONAL PERFORMANCE AND SPATIAL CONVERGENCE IN PERU [PDF]
While an enormous and growing literature exists on the topic of re-gional income convergence, other aspects of socioeconomic well-being and development have attracted much less attention. Social indicators are a valuable complement to economic indicators
Maribel ELIAS, Sergio J. REY
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
ON POTENTIALIZED PARTIAL FINITE DIFFERENCE EQUATIONS: ANALYZING THE COMPLEXITY OF KNOWLEDGE-BASED SPATIAL ECONOMIC DEVELOPMENTS [PDF]
Knowledge-based regional and urban studies are plentiful; some systematics might be in order at this junction, so first the different links between economic production units in geographical space have to be clearly defined.
Alain SALLEZ +3 more
core