Results 31 to 40 of about 40,279 (236)
The Victoria, Mexico, Earthquake of June 9, 1980
El sismo de Victoria de junio 9 de 1980 (ML = 6.1) ocurrió en el Valle de Mexicali cerca de la traza de la falla de Cerro Prieto con un mecanismo focal de fallamiento de rumbo con movimiento lateral derecho en un plano vertical.
V. Wong, J. Frez, F. Suarez
doaj +1 more source
Análisis estadístico y comportamiento fractal de las réplicas sísmicas del Sur de California [PDF]
Mediante el análisis estadístico y utilizando diversas técnicas fractales en esta tesis se estudia el comportamiento temporal y espacial de tres series de réplicas sísmicas ocurridas en el Sur de California, que tuvieron lugar después de los terremotos ...
Monterrubio Velasco, Marisol
core +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Teens, manga and replica shabtis
The Teens, Manga and Digitally Produced Replicas Project, which brings together archaeologically charged replicas, members of the ‘youth generation community’ and manga cartoons, forms part of PhD research at the Institute of Archaeology.
doaj +2 more sources
Estratégia Reativa e Orientada a Eventos para o Balanceamento de Réplicas em um Cluster HDFS
International audienceO HDFS Balancer é a solução oficial para o balanceamento de réplicas no sistema de arquivos distribuído do Hadoop (HDFS). Atualmente, é responsabilidade do administrador do cluster monitorar o estado do sistema e, quando julgar ...
Fazul, Rhauani Weber Aita +1 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source

