Results 61 to 70 of about 45,350 (227)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Avaliação e comparação de diversas réplicas de dentes utilizados para tratamento endodôntico em pré-clínico [PDF]
, 2017 Dissertação para obtenção do grau de Mestre no Instituto Superior de Ciências da Saúde Egas MonizIntrodução: O ensino e consequente aprendizagem do tratamento endodontico, mais especificamente a preparação química e mecânica dos canais radiculares ...
Fochuk, Lyudmyla
core
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Sobre movilidad de réplicas [PDF]
, 2001 El objetivo de este trabajo es desarrollar un protocolo que permita la movilidad de una réplica. El protocolo no permite más de tres migraciones dinámica de una réplica, y obliga una permanencia estable de ésta en su nueva locación por un tiempo ...
Ardenghi, Jorge Raúl +2 more
core
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Cinco réplicas de un estudio: parametrización y ANOVA
, 2020 Diseños de investigación en Psicología, Innovando durante el COVID-19 con video-explicaciones discentes. Raquel Dawra Wehbe.
García, Fernando
core
Dotación de infraestructura básica en laboratorio para realizar metalografía de campo mediante réplicas [PDF]
, 2013 Este trabajo trata sobre la construcción de una infraestructura básica en el laboratorio de materiales de la Facultad de Ingeniería Mecánica, que permita a los estudiantes poder realizar prácticas académicas sobre metalografía de campo mediante el uso de
Encarnación Vera, Jorge Vladimir
core
PLoS ONE, 2020 Scanning electron microscopy (SEM) is widely used to investigate the surface morphology, and physiological state of plant leaves. Conventionally used methods for sample preparation are invasive, irreversible, require skill and expensive equipment, and ...
William J Matthaeus +3 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source