Results 201 to 210 of about 3,095,409 (252)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Mapping the Insecticide Resistance Landscape of Malaria Vectors in Odisha, India (1993-2024): A Scoping Review. [PDF]

J Trop Med
Barik TK, Velamuri PS, Bhuyan KB, Sabar S, Mohapatra P, Sahu B, Das MK, Pati S, Dash AP, Raghavendra K.   +9 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Occurrence of oxazolidinone resistance genes in enterococci, staphylococci, and Mammaliicoccus sciuri from swine slaughterhouse wastewater, Italy. [PDF]

World J Microbiol Biotechnol
Massacci FR, Simoni S, Albini E, Nigro ME, Russo E, D'achille G, Paoletti C, Morroni G, Mingoia M, Zhu Y, Zhang W, Vignaroli C, Magistrali CF, Giovanetti E, Brenciani A.   +14 more
europepmc   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Electrohydrodynamic printed ultra-high performance liquid metal strain sensor. [PDF]

Microsyst Nanoeng
Chen X, Feng Y, Chen K, Li Z, Liu C, Chen X, Wang Z, Zhang X, Zhang R, Liu S, Gao X, Li W, Wang T, Wang D.   +13 more
europepmc   +1 more source

PIP - Itinéraire technique mangue (Mangifera indica) [PDF]

, 2013
Maraite, Henri, Rey, Jean-Yves, Vannière, Henri, Vayssières, Jean-François   +3 more
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Dynamic regression forecasting of carbapenem-resistant Klebsiella spp. based on carbapenem consumption with observed data from 2020 to 2023 and projections up to 2029 in a tertiary hospital in Alexandria, Egypt. [PDF]

BMC Infect Dis
Elmongui E, Zaki A, Elsheredy A, Elhameed AA.   +3 more
europepmc   +1 more source