Results 111 to 120 of about 4,089 (272)

Periodic solutions for some partial neutral functional differential equations

open access: yesElectronic Journal of Differential Equations, 2006
In this work, we study the existence of periodic solutions for partial neutral functional differential equation. We assume that the linear part is not necessarily densely defined and satisfies the Hille-Yosida condition.
Rachid Benkhalti   +2 more
doaj  

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

Some qualitative properties of Lichnerowicz equations and Ginzburg–Landau systems on locally finite graphs

open access: yesComptes Rendus. Mathématique
Let $(V,E)$ be a locally finite weighted graph. We study some qualitative properties of positive solutions of the Lichnerowicz equation \[ v_t-\Delta v=v^{-p-2}-v^p, \;(x,t)\in V \times \mathbb{R}, \] and of (sign-changing) solutions of the Ginzburg ...
Duong, Anh Tuan, Fujiié, Setsuro
doaj   +1 more source

Maximal Regularity of the Discrete Harmonic Oscillator Equation

open access: yesAdvances in Difference Equations, 2009
We give a representation of the solution for the best approximation of the harmonic oscillator equation formulated in a general Banach space setting, and a characterization of lp-maximal regularity—or well posedness—solely in terms of R ...
Airton Castro   +2 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Generalized Carleson Measure Spaces and Their Applications

open access: yesAbstract and Applied Analysis, 2012
We introduce the generalized Carleson measure spaces CMOrα,q that extend BMO.
Chin-Cheng Lin, Kunchuan Wang
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

open access: yesFEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng   +2 more
wiley   +1 more source

R-boundedness [PDF]

open access: yes, 2017
Tuomas Hytönen   +3 more
openaire   +1 more source

Home - About - Disclaimer - Privacy