Results 21 to 30 of about 3,553,280 (245)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Systems Approach Reveals Nuclear Factor Erythroid 2-Related Factor 2/Protein Kinase R Crosstalk in Human Cutaneous Leishmaniasis

open access: yesFrontiers in Immunology, 2017
Leishmania parasites infect macrophages, causing a wide spectrum of human diseases, from cutaneous to visceral forms. In search of novel therapeutic targets, we performed comprehensive in vitro and ex vivo mapping of the signaling pathways upstream and ...
Áislan de Carvalho Vivarini   +12 more
doaj   +1 more source

FLRW Cosmology with Hybrid Scale Factor in f(R, Lm) Gravity

open access: yesEast European Journal of Physics, 2023
In this paper, we aim to describe the cosmic late-time acceleration of the Universe in f(R,Lm) gravity framework proposed by Harko (2010) with the help of an equation of state for strange quark matter. To achieve this, we adopt a specific form of f(R,Lm)
Vasudeo Patil   +3 more
doaj   +1 more source

Trimethoprim Resistance determined by R Factors [PDF]

open access: yesBMJ, 1972
R factors conferring a high level of resistance to trimethoprim have been identified in one strain of Escherichia coli and one of Klebsiella aerogenes , both isolated from infected urines.
M P, Fleming, N, Datta, R N, Grüneberg
openaire   +2 more sources

Health‐Related Social Needs in Children With Sickle Cell Disease Are Associated With Worse Health‐Related Quality of Life

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell disease (SCD) face multiple acute and chronic medical complications that may impact their quality of life as reported by patients themselves. Health‐related social needs (HRSNs), such as food and housing insecurity, are common in people with SCD, but the association between HRSNs and patient‐reported ...
Sarah J. Marks   +5 more
wiley   +1 more source

Structure of R&D capital expenditure and national total factor productivity

open access: yesCogent Economics & Finance, 2023
This paper examines the relationship between the structure of R&D fixed capital spending, measured as the ratio of the private sector to public sector R&D capital expenditure, and national total factor productivity.
Juniours Marire
doaj   +1 more source

R factors from Providence [PDF]

open access: yesMicrobiology, 2000
Of more than 100 R factors transferred from naturally occurring Providence strains, approximately 60 % belonged to the A-C compatibility complex. Plasmids of groups F1, J, N, P and X, and the prototype of a new group G were also transferred. The Providence R factor set differs from those of Proteus rettgeri and P.
openaire   +2 more sources

Cup‐Like Nuclei Is a Hallmark of DUX4/ERG Acute Lymphoblastic Leukemia and Reveals Cytoplasmic Mitochondria Accumulation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille   +9 more
wiley   +1 more source

Origin of Haemophilus influenzae R factors [PDF]

open access: yesJournal of Bacteriology, 1981
The Haemophilus influenzae R plasmids specifying resistance against one, two, or three antibiotics which have emerged in different parts of the world were shown to have closely related but not identical plasmid cores. The gene for ampicillin resistance in the H.
R, Laufs   +4 more
openaire   +2 more sources

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger   +7 more
wiley   +1 more source

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