Results 231 to 240 of about 15,790,043 (329)

Community engagement studios to improve racial diversity and health equity in Parkinson's. [PDF]

open access: yesJ Clin Transl Sci
Kang E   +8 more
europepmc   +1 more source

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

open access: yesAdvanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang   +12 more
wiley   +1 more source

Reprogramming M2b Macrophages via GPX1 Activation by Selenium Nanoparticles Attenuates Lupus Nephritis

open access: yesAdvanced Science, EarlyView.
SeZM NPs selectively target M2b macrophages through mannose–MRC1 (CD206) recognition, enhance GPX1 biosynthesis, and suppress mitochondrial ROS generation, oxidative stress, and JAK–STAT signaling. This dual regulation reduces pro‐inflammatory cytokine release, limits immune cell infiltration and fibrosis, and preserves renal function, providing a ...
Haoran Lv   +16 more
wiley   +1 more source

Engineered Interpenetrating MXene Networks in Aramid Layered Films for Antioxidant and Broadband Electromagnetic Interference Shielding

open access: yesAdvanced Science, EarlyView.
This study introduces an innovative interpenetrating layered structure, comprising alternating aramid nanofiber (ANF) layers and MXene layers, fabricated through a directional freeze–thaw intercalation–gel‐film formation strategy. Unlike traditional homogeneous layered films, this unique layered structure features mutually embedded conductive and ...
Hongli Cheng   +9 more
wiley   +1 more source

Structural and Mechanical Dynamics of Polymer Membranes Across Multilength Scales

open access: yesAdvanced Science, EarlyView.
Distinct surface‐to‐bulk mechanical contrasts in polymer membranes were unveiled, highlighting the need to probe both regions to fully capture their functional behavior. By integrating in situ SAXS–WAXS with AFM‐based nanomechanics, nanodomain‐level heterogeneity and real‐time structural transformations induced by thermal and mechanical stimuli were ...
Rifan Hardian   +6 more
wiley   +1 more source

Single‐Crystal PZT‐Driven Organic Piezo‐Phototronic Adaptive Transistors Toward Advanced Spatiotemporal Visual Computing

open access: yesAdvanced Science, EarlyView.
Here, we propose a single‐crystal PZT‐based piezo‐phototronic organic adaptive memory transistor (OAMT), achieving a record memory window capacity factor (γ) of 0.87 at a low SS of 200 mV/decade via efficient multi‐field control. The device achieves a high recognition accuracy ∼ 90% in neuromorphic simulations, demonstrates robust fault tolerance under
Chenhao Xu   +8 more
wiley   +1 more source

Luspatercept for the treatment of transfusion-dependent non-severe aplastic anemia. [PDF]

open access: yesAnn Hematol
Jia X   +7 more
europepmc   +1 more source

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