Results 271 to 280 of about 11,560,820 (354)

Climate indirectly modulates tree survival of spruce beetle attacks via effects on constitutive and induced secondary metabolites. [PDF]

Front Plant Sci
Khedive E, Fathi Moghanloo S, Davis TS.
europepmc   +1 more source

Discovery and Engineering of a Rat Endogenous Retrovirus Reverse Transcriptase for Efficient Prime Editing

Advanced Science, EarlyView.
We screened 558 reverse transcriptases and engineered an optimized rat endogenous retrovirus‐derived variant, enRERV‐RT, via structure‐guided engineering and deep mutational scanning. This enhanced prime editor, based on the engineered RT, outperforms conventional M‐MLV‐RT systems across plant and animal cells, particularly at hard‐to‐edit loci ...
Linsha Ma, Pengcheng Yao, Shengqi Wu, Yuanyuan Shi, Lang Qin, Baitao Li, Jiayi Zhu, Minhua Huang, Yichong Zhu, Yuwen Song, Jinhuan Pang, Ziping Guo, Guochuan Wu, Chen Wang, Kewei Xu, Ruihua Huang, Quan Kuang, Liang Qu, Changtian Pan, Xianrong Xie, Qinlong Zhu, Jiaying Huang, Qiupeng Lin   +22 more
wiley   +1 more source

AI‐Designed Cyclic Peptides Enable Controllable Modulation of the CD28 Immune Checkpoint

Advanced Science, EarlyView.
AI‐designed cyclic peptides enable controllable modulation of the CD28 immune checkpoint through reversible disruption of CD28‐CD80/CD86 interactions. The lead peptide, CIP‐3, suppresses T‐cell activation without intrinsic agonist activity, demonstrates dose‐dependent efficacy in a murine colitis model, and attenuates inflammatory cytokine production ...
Katarzyna Kuncewicz, Saurabh Upadhyay, Renjie Zhu, Hongliang Duan, Moustafa T. Gabr   +4 more
wiley   +1 more source

Persistent conflict in palaeognath phylogeny revealed by quartet-based and ML analyses. [PDF]

Front Zool
Kück P, Suh A.
europepmc   +1 more source

Winter sanitation and ground management practices for navel orangeworm (Lepidoptera: Pyralidae) control in pistachios. [PDF]

J Econ Entomol
Daane KM, Yokota GY, Krugner R, Siegel JP, Haviland DR, Wilson H, Burks CS.   +6 more
europepmc   +1 more source

Aboveground biomass in seven tropical forest patches of Western-Africa: comparison of manual inventory and terrestrial laser scanning. [PDF]

Ann For Sci
Hepner S, Agonvonon GA, Kükenbrink D, Iheaturu C, Azihou F, Sinsin B, Ifejika Speranza C.   +6 more
europepmc   +1 more source

Detecting apple replant disease in the field - deciphering reasons for local growth depression. [PDF]

PLoS One
Wachter AS, Hauschild K, Liu B, Schnoor P, Bloem E, Wrede A, Hornig R, Beerhues L, Schlüter S, Smalla K, Winkelmann T, Vetterlein D.   +11 more
europepmc   +1 more source

Functional Diversity and Community Composition of Soil Fungi Associated With Canopy Dieback in Araucaria araucana Forests of Contrasting Edaphic Conditions. [PDF]

Environ Microbiol Rep
Arriagada V, Garrido A, Madariaga F, Hasbun R, Sanfuentes E.   +4 more
europepmc   +1 more source