Results 121 to 130 of about 264,021 (301)

Interleukin‐37 Enhances Liver NK Cell Cytotoxicity and Improves Recurrence‐Free Survival in Hepatocellular Carcinoma Patients

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Introduction Hepatocellular carcinoma (HCC) remains a major cause of cancer‐related mortality worldwide, and postoperative recurrence continues to limit long‐term survival. Liver‐resident natural killer (NK) cells are key effectors of antitumor immunity in the hepatic microenvironment. Interleukin‐37 (IL‐37), an anti‐inflammatory cytokine, has
Yuki Imaoka, Masahiro Ohira, Yuka Tanaka, Toshihiro Nakayama, Miho Akabane, Shinichiro Yokota, Sheri M. Krams, Olivia M. Martinez, Carlos O. Esquivel, Kazunari Sasaki, Hideki Ohdan   +10 more
wiley   +1 more source

Neoadjuvant radiotherapy combined with targeted and immune therapies achieves a pathological complete response in borderline resectable gallbladder cancer: a case report and literature review

Frontiers in Oncology
BackgroundGallbladder cancer, a malignant tumor with a notable prevalence, is primarily treated with surgical R0 resection, which remains the most efficacious therapeutic strategy.
Tao Li, Zhiqin Li, Keren Li, Gong Li, Guangxin Li, Ying Zhao   +5 more
doaj   +1 more source

Does the revised cardiac risk index predict cardiac complications following elective lung resection? [PDF]

, 2013
Background: Revised Cardiac Risk Index (RCRI) score and Thoracic Revised Cardiac Risk Index (ThRCRI) score were developed to predict the risks of postoperative major cardiac complications in generic surgical population and thoracic surgery respectively.
Pala Rajesh, Naidu, Babu V, Babu Naidu, Marshall, Andrea, Bishay, Ehab, Maninder Kalkat, Ehab Bishay, Kerr, Amy, Richard Steyn, Wotton, Robin, Kalkat, Maninder, Steyn, Richard, Naidu, Babu, Rajesh, Pala B, Amy Kerr, Andrea Marshall, Kalkat, Maninder S, Marshall, A. (Andrea), Rajesh, Pala, Robin Wotton   +19 more
core   +2 more sources

Routine MDM2 FISH Testing and Preoperative Biopsy Reduces Recurrence Rate of Atypical Lipomatous Tumours

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background Although MDM2 FISH test has been increasingly used to differentiate ALT and benign lipomatous tumours, its impact on clinical outcome remains underexplored. This study investigated whether routine MDM2 FISH testing on preoperative biopsy is associated with a reduction in the recurrence risk of ALT.
Samuel O. H. Ching, Anderson S. M. Leung, Raymond C. H. Yau, Albert Y. L. Lam, Tony W. H. Shek, Maximus C. F. Yeung   +5 more
wiley   +1 more source

Retrohepatic Vena Cava Encirclement, as Surrogate of Extensive Liver Manipulation During Caval Sparing Hepatectomy, Is a Risk Factor for Tumor Recurrence After Liver Transplantation for Hepatocellular Carcinoma

Journal of Surgical Oncology, EarlyView.
ABSTRACT Introduction In liver transplantation (LT) with a caval sparing (CS) approach, the presence of complete encirclement of inferior vena cava (IVC‐E) by hypertrophic segment 1 increases the technical complexity of hepatectomy. Thus, in LT for hepatocellular carcinoma (HCC), It may be suspected that the resulting greater liver manipulation and ...
Riccardo Pravisani, Claudio Bosio, Grazia Conte, Alex Borin, Amedeo Carraro, Federico Mocchegiani, Maria De Martino, Marco Vivarelli, Dario Lorenzin, Umberto Baccarani   +9 more
wiley   +1 more source

Outcomes Following Total Pancreatectomy With and Without Vascular Resection: A NSQIP Analysis Comparing Trends in Patient Selection and Outcomes Over 5 Years

Journal of Surgical Oncology, EarlyView.
ABSTRACT Introduction Advances in neoadjuvant therapy and surgical techniques have led to more total pancreatectomies (TP) with vascular resection for pancreatic cancer. This study assesses contemporary outcomes of TP with venous (VR) and arterial (AR) resections compared to non‐vascular resection (NVR).
Zofia Czarnecka, Kevin Verhoeff, A. M. James Shapiro, Chaya Shwaartz   +3 more
wiley   +1 more source

Forest plots of R0 resection rate in patients with neoadjuvant therapy versus those surgery first.

It showed that neoadjuvant therapy significantly increased the R0 resection rate compared to surgery alone.
Ding Cao (1438294), Fucai Yu (17290924), Lu Huan (18121144), Maoling Qin (18121147), Hantao Zhou (8641185), Yang Cao (53545)   +5 more
core   +1 more source

Potential of surgery and chemotherapy in patients with second metastatic recurrence after R0-resection of colorectal liver metastases.

, 2012
644 Background: Surgical resection is the standard of care for resectable colorectal metastases (CRM). Preoperative chemotherapy allows assessment of tumorbiology and has been shown to convert approximately 30% of unresectable patients into secondary ...
Martin Niessner, Annalen Bleckmann, Michael B. Ghadimi, Kia Homayounfar, Lena Conradi, Thilo Sprenger, Heinz Becker, Torsten Liersch, Thomas Lorf   +8 more
core   +1 more source

Neoadjuvant Radiotherapy is Associated with R0 Resection and Improved Survival for Patients with Extremity Soft Tissue Sarcoma Undergoing Surgery: A National Cancer Database Analysis [PDF]

, 2017
BackgroundNeoadjuvant radiotherapy (RT) is increasingly advocated for the management of soft tissue sarcoma (STS). Therefore, this study sought to characterize the impact of neoadjuvant RT on rates of R0 resection and overall survival (OS) in extremity ...
Morgan A. Darrow, Robert J. Canter, Thorpe, Steven W, Darrow, Morgan A, Bold, Richard J, Sarah B. Bateni, Bateni, Sarah B, Gingrich, Alicia A, Kirane, Amanda R, Arta M. Monjazeb, Monjazeb, Arta M, Steven W. Thorpe, Amanda R. Kirane, Alicia A. Gingrich, Richard J. Bold, Canter, Robert J   +15 more
core   +1 more source

Walking to the Operating Room: A Qualitative Study of Colorectal Cancer Patient Experiences in a Dutch Academic Hospital

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives This study explores experiences of colorectal cancer (CRC) patients with the Surgery on Foot (SOF) protocol. In contrast to patients being admitted to the hospital the night before surgery, these patients arrive at the hospital on the day of surgery, walk to the operating room, and lie down on the operating table for ...
Ise S. M. van Gool, Jip van der Klugt, Christel Gielen, Ghislaine A. P. G. van Mastrigt, Francine Schneider, Merel L. Kimman, Arnoud G. Peppelenbosch, Tim Lubbers   +7 more
wiley   +1 more source