Results 101 to 110 of about 18,465 (221)
Organic and Metallacages for Chemical Sensing: Progress in Water‐Compatible Systems
Supramolecular cages function as three‐dimensional receptors for selective molecular recognition and sensing, and this review outlines design principles for water‐stable architectures, key analyte‐ and medium‐dependent challenges, recent water‐compatible examples (including polymer‐integrated systems), and future opportunities for cage‐based ...
Rabia Zahid +4 more
wiley +1 more source
High light exposure triggers an epidermis‐specific remodeling of mitochondria and ER in Arabidopsis, driven by chloroplast‐derived signals. Live‐cell imaging shows that HL rapidly suppresses mitochondrial motility, followed by fusion‐driven elongation and ER cisternal expansion.
Evan R. Angelos +12 more
wiley +1 more source
Nanoparticle Immunoadjuvant Complexes Augment Germinal Center Responses to Vaccination
Scaffolding IL‐21 on the surface of a self‐assembling nanoparticle immunogen drives improved germinal center and humoral immune responses. These nanoparticle immunoadjuvant complexes (NICs) functionally modulate the germinal center driving improved somatic hypermutation and antibody maturation, suggesting this platform has potential utility as a ...
Nicholas J. Tursi +21 more
wiley +1 more source
Click Chemistry and Bioorthogonal Reaction for Aggregation‐Induced Emission Bioconjugates
This review highlights the construction of AIE active bioconjugates via click chemical or bioorthogonal reactions, and their applications in biosensing, bioimaging, and image‐guided treatment. The challenges and perspectives in the area are also discussed.
Xinzhe Yang +3 more
wiley +1 more source
Abstract INTRODUCTION Cerebral small vessel disease (CSVD) contributes to the development of Alzheimer's disease (AD) dementia and co‐occurs with AD‐associated proteinopathies. However, how sex modulates the interaction between CSVD and AD‐associated proteinopathies in the medial temporal lobe (MTL) remains unclear.
Francesco Bax +14 more
wiley +1 more source
Our analysis revealed numerous differentially expressed genes between Alzheimer's disease (AD) patients and controls, identifying 29 AD‐related genes, with 21 linked to cholesterol metabolism, underscoring its key role in AD pathogenesis. We developed a robust 8‐gene diagnostic signature that surpassed existing AD diagnostic models in both training and
Rui Sun +8 more
wiley +1 more source
Flipping the Switch: Next‐Generation Chemo‐Optogenetics for Reversible Control of Biological Systems
Next‐generation chemo‐optogenetic systems use photoswitchable molecular glues for reversible, repeatable light control of protein proximity, enabling precise spatiotemporal modulation of signaling, organelle dynamics, and protein stability—opening avenues for in vivo studies and therapeutic applications.
Laura K. Herzog, Jun Zhang, Yao‐Wen Wu
wiley +1 more source
The native‐dominated vegetation on roadside slopes primarily originates from adjacent forests, with long‐distance dispersal traits enhancing spontaneous colonization in these disturbed environments. The species composition and phylogenetic similarity between slope and forest communities are significantly influenced by the adjacent forests (species ...
Kun‐Rong Qin +5 more
wiley +1 more source

