Results 101 to 110 of about 23,845 (249)

Macrophage Lipid Homeostasis Drives IVDD via a Senescence‐Dependent Impairment of Efferocytosis

Cell Proliferation, EarlyView.
Intervertebral disc degeneration (IVDD) has been a leading cause of low back pain and lacks disease‐modifying therapies. Although dysregulated disc lipid metabolism is implicated, its impact on the immune microenvironment, particularly macrophages, remains unknown.
Jinyu Wang, Shiyong Ling, Qi Wang, Xuege Qiao, Jianpeng Xing, Siyang Ji, Linhui Han, Chen Yan, Zhishen Niu, Lei Yuan, Baolian Zhao, Kaiqiang Sun, Jiangang Shi   +12 more
wiley   +1 more source

A PD1‐CD137L Fusion Protein More Potently Enhances Anti‐Tumour Immune Responses Than Targeting PD‐L1 and CD137 Separately

Immunology, EarlyView.
A PD1‐CD137L fusion protein converts the immunoinhibitory PD‐L1 to an immunostimulatory signal and is more effective than targeting PD‐L1 and CD137 separately. ABSTRACT Tumour immune evasion frequently involves PD‐L1‐mediated inhibition of T cell activity, limiting the efficacy of PD1/PD‐L1 blockade, particularly in PD‐L1‐low or immunologically ‘cold ...
Runze Xia, Emily Pauline Nickles, Yu Mei, Thamizhanban Manoharan, Yi Tian Png, Beijia Liu, Rui Sun, Kang Yi Lee, Gloryn Chia, Chwee Ming Lim, Herbert Schwarz   +10 more
wiley   +1 more source

SERVIR West Africa 2025 Training Program on Data Stewardship and the CoreTrustSeal Requirements: Session 2, R09, R10 & R11 Requirements [PDF]

Preparing an application for CoreTrustSeal Certification provides the repository with an opportunity to ensure that it has established a plan for the preservation of its holdings, capabilities for assuring their quality, and a workflow that enables the ...
Downs, Robert R.
core   +1 more source

Challenging Host Specificity: Malacosporean Parasite Dynamics—Tetracapsuloides bryosalmonae Beyond Salmonids—An Infection Experiment

Journal of Fish Diseases, EarlyView.
ABSTRACT Proliferative Kidney Disease (PKD) is a severe parasitic disease of salmonids caused by the malacosporean endoparasite Tetracapsuloides bryosalmonae. In the fish intermediate host, the parasite is disseminated via the circulatory system and ultimately reaches the kidney, where it matures before releasing infective spores into the environment ...
Céline Möckli, Nicolas Diserens, Gary Delalay, Gastón Moré, Heike Schmidt‐Posthaus   +4 more
wiley   +1 more source

Effects of LED light combinations on the growth and postharvest stability of barley grass (Hordeum vulgare L.) cultivated in a plant factory system

Notulae Botanicae Horti Agrobotanici Cluj-Napoca
This study examined the effects of various LED light combinations on the germination, growth, and photosynthetic efficiency of barley grass (Hordeum vulgare L.) cultivated in a plant factory system, and evaluated how different postharvest packaging ...
Si-Hong KIM, Ho-Min KANG
doaj   +1 more source

RTK-måling med tilt-kompensasjon: Sammenligning av Trimble R12i og Trimble R10, samt ytelsesevaluering av tilt-sensor i R12i [PDF]

Denne masteroppgaven undersøker hvordan Trimble R12i presterer sammenlignet med Trimble R10, med fokus på nøyaktighet og presisjon i RTK-målinger under varierende måleforhold.
Mikalsen, Magnus Hole
core  

Lymphocystis Disease in Endemic Aotearoa New Zealand Bully (Gobiomorphus cotidianus)

Journal of Fish Diseases, EarlyView.
ABSTRACT We detected lymphocystis disease virus (LCDV) for the first time in an Aotearoa New Zealand freshwater environment, from an individual common bully, toitoi, Gobiomorphus cotidianus (Eleotridae). Dinah's bully, Gobiomorphus dinae, and Kaharore bully, Gobiomorphus mataraerore, also exhibited gross nodular lesions on the fins but were not sampled.
Kate S. Hutson, Karthiga Kumanan, Anne Rolton, Emily C. Giles, Joy A. Becker, Maeve Ballantyne, Tim Hewison, Georgia S. Steel, Joshua Wardle, Ashley Webby, Bram T. M. Mulling   +10 more
wiley   +1 more source

Anatomy of spinal CSF loss in the American alligator (Alligator mississippiensis)

Journal of Anatomy, Volume 246, Issue 4, Page 575-584, April 2025.
India ink introduced into the cranial cerebrospinal fluid (CSF) compartment of Alligator diffuses along the spinal cord and exits the spinal compartment using perineural flow, resulting in a prominent “ink cuff” forming at the base of the spinal nerve. In Alligator, the region of the ink cuff is drained by a small lymphatic vessel.
Hadyn DeLeeuw, Michael Cramberg, Matthew Dille, Emily Pick, Mary Thompson, Bruce A. Young   +5 more
wiley   +1 more source

Pharmacological Targets for Periodontitis: A Systematic Review of Drug‐Target Mendelian Randomisation Studies

Journal of Periodontal Research, EarlyView.
This systematic review evaluated drug‐target Mendelian randomisation studies on periodontitis. Twelve studies identified host‐response‐related targets mainly involved in inflammatory, complement, and immune pathways. Although some targets were linked to existing drugs, the evidence remains preliminary and heterogeneous, requiring replication and ...
Luigi Nibali, Jing Kang, Simon Haworth, Alessandro Polizzi, Gaetano Isola   +4 more
wiley   +1 more source

HIGH GLUCOSE CONCENTRATION INCREASES THE M2 PROFILE AND REDUCES THE MICROBICIDAL ACTIVITY OF MACROPHAGES CHALLENGED WITH ENCEPHALITOZOON CUNICULI

Brazilian Journal of Infectious Diseases
Introduction: Hyperglycemia, an alteration seen in diabetes, causes changes in the immune response and increases the susceptibility of diabetic individuals to infections. In macrophages cultured in high glucose (HG), changes in metabolism, phenotype, and
Elisangela Pinto, Juliana Braga Gomes, Anuska Marcelino Alvares Saraiva, Elizabeth Cristina Peres, Maria Anete Lallo   +4 more
doaj   +1 more source