Results 41 to 50 of about 888,139 (241)

Influenza as a Cause of SIADH Related Hyponatremia: A Case Report [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Syndrome of Inappropriate Secretion of Antidiuretic Hormone (SIADH) is one of the most common causes of hyponatremia in hospitalized patients. The distinct aetiologies and co-morbidities associated with hyponatremia pose substantial challenges in ...
Bhavita Gaglani   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Life Situation of Polish Seniors – Their Subjective Assessment

open access: yesFolia Oeconomica Stetinensia
Seniors wield influence across a spectrum of social spheres. Understanding their attitudes, needs, challenges, and expectations emerges as imperative for shaping effective social policies and social inclusion. Their significant heterogeneity necessitates
Przybysz Klaudia, Stanimir Agnieszka
doaj   +1 more source

Entrepreneurial Orientation, Technology Orientation and Small and Medium Enterprises Performance in Nigeria: Role of Government Support Policies

open access: yesJournal of Business and Social Review in Emerging Economies, 2017
Purpose: The study empirically analyzes the moderating role of government support policy on the relationship between entrepreneurial orientation, technology orientation, and performance of small and medium enterprises (SMEs) in northeast Nigeria ...
Maryam Imam Ibrahim   +2 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Constructing a Corrected Stations Network Using Some Geomatic Techniques

open access: yesCivil and Environmental Engineering
The major objective of this study is to establish a network of Ground Control Points-GCPs which can use it as a reference for any engineering project.
Ali Amal Mahdi   +2 more
doaj   +1 more source

Prediction of Rice Production to Support Food Security in Bogor Regency using Linear Regression and Support Vector Machine (SVM)

open access: yesJurnal Teknika
A prediction is an estimation of something that has not yet occurred. Its purpose is to minimize uncertainty and reduce errors in planning. Bogor Regency, with the largest population in West Java, requires a substantial amount of food.
Ani Apriani   +2 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

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