Results 81 to 90 of about 248,956 (214)

Investigating transthyretin variants H88R and I107V in amyloid priming: From destabilization to complete dissociation

The FEBS Journal, EarlyView.
Investigated mutations in transthyretin (TTR) disrupt the F87‐centered hydrophobic core that stabilizes its tetrameric structure. The mild I107V mutation weakens inter‐chain packing, while H88R fully abolishes tetramer formation, yielding a monomeric, aggregation‐prone form. Structural, biophysical, and computational analyses reveal that both mutations
István L. Bódy, Zsolt Fazekas, Nóra Wágner, Anna J. Kiss‐Szemán, Veronika Harmat, Zoltán Pozsonyi, Dóra K. Menyhárd, András Perczel   +7 more
wiley   +1 more source

Functional characterization of 42 CK2α de novo variants associated with Okur‐Chung neurodevelopmental syndrome

The FEBS Journal, EarlyView.
Okur‐Chung neurodevelopmental syndrome (OCNDS) is a neurodevelopmental disorder associated with mutations in the gene coding for Protein kinase CK2α. In this work, 42 variants of CK2α associated with OCNDS were characterized in vitro. This included determination of catalytic activity and CK2α/CK2β‐interaction as well as an assessment of evolutionary ...
Alexander Gast, Christian Werner, Karsten Niefind, Joachim Jose   +3 more
wiley   +1 more source

R21 vaccine

Asian Pacific Journal of Tropical Medicine, 2023
Nitika Nitika, Shrikant Nema, Praveen Kumar Bharti   +2 more
openaire   +2 more sources

Reading Fluency Matters: NIH R21 HD090460-01A1

, 2018
Fluency is an essential feature of skilled reading. Reading speed is an overt reflection of automaticity in decoding and similarly deft control over other component skills. There is considerable support for oral reading speed as a valid and reliable indicator of general reading skill.
Nam, Hosung, Gong, Tao, Braze, David
openaire   +3 more sources

Post‐Release Survival of the Pelagic Stingray (Pteroplatytrygon violacea, Bonaparte, 1832) in French Longline Fisheries in the Northwestern Mediterranean Sea

Fisheries Management and Ecology, EarlyView.
ABSTRACT Bycatch remains a critical challenge in global fisheries, even when using selective gears such as longlines. In the French longline fishery targeting Atlantic bluefin tuna (Thunnus thynnus) in the Gulf of Lion, the common pelagic stingray (Pteroplatytrygon violacea) is the primary bycatch species.
Antoine Landreau, Vincent Kerzérho, Olivier Derridj, Bertrand Wendling, Nolwenn Cosnard, Tristan Rouyer   +5 more
wiley   +1 more source

Reward‐specific learning parameters change across normative adolescent development and are blunted in youth with high risk for depression

Journal of Child Psychology and Psychiatry, EarlyView.
Background Reward learning is thought to undergo refinement in adolescence, but little is known about how computational components of reinforcement learning develop. Given that adolescence is a sensitive period for reward system plasticity with associated vulnerability for depression, it is important to understand developmental trajectories of ...
Holly Sullivan‐Toole, Jeremy M. Haynes, Helen Schmidt, Bart Larsen, Nathaniel Haines, Thomas M. Olino   +5 more
wiley   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, EarlyView.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source

Linear Stability of Triangular Equilibrium Points in the Generalized Photogravitational Restricted Three Body Problem with Poynting-Robertson Drag

, 2006
In this paper we have examined the linear stability of triangular equilibrium points in the generalised photogravitational restricted three body problem with Poynting-Robertson drag.
Chernikov Yu.A., Colombo G.D. Lautman, Ishwar B., Kushvah B.S., Liou J.C., McCuskey S.W., Murray C.D., O’Neill G. K., Poincare H., Ragos O., Robertson H.P., Sahoo S.K., Schuerman D.W., Singh J., Tripathi Deepak Kumar, Wyatt S.P.   +15 more
core   +4 more sources

Spectral density of mixtures of random density matrices for qubits

, 2018
We derive the spectral density of the equiprobable mixture of two random density matrices of a two-level quantum system. We also work out the spectral density of mixture under the so-called quantum addition rule.
Chen, Zhihua, Wang, Jiamei, Zhang, Lin
core   +1 more source

Low‐Cost and Detunable Wireless Resonator Glasses for Enhanced Eye MRI With Concurrent High‐Quality Whole‐Brain MRI

Magnetic Resonance in Medicine, Volume 96, Issue 1, Page 499-507, July 2026.
ABSTRACT Purpose To develop a wearable wireless resonator glasses design that enhances eye MRI signal‐to‐noise ratio (SNR) without compromising whole‐brain image quality at 7 T. Methods The device integrates two detunable LC loop resonators into a lightweight, 3D‐printed frame positioned near the eyes.
Ming Lu, Xiaoyue Yang, Jason E. Moore, Pingping Li, Adam W. Anderson, John C. Gore, Seth A. Smith, Xinqiang Yan   +7 more
wiley   +1 more source