Inhibition of HER2 signaling and breast cancer cell growth with a novel antibody targeting HER2 ECD III/IV. [PDF]
PLoS ONEHuman epidermal growth factor receptor 2 (HER2), a ligand-independent tyrosine kinase receptor belonging to the EGFR family, serves as a key oncogenic driver in breast, gastric, and several other solid tumors.
Chunchun Liu +10 more
doaj +2 more sources
Identification and Analysis of Antimicrobial Activities from a Model Moss Ceratodon purpureus
Metabolites, 2023 The emergence of bacterial drug resistance is often viewed as the next great health crisis of our time. While more antimicrobial agents are urgently needed, very few new antibiotics are currently in the production pipeline.
Ashley L. Dague +6 more
doaj +2 more sources
Epidemiological evidence for the role of puberty and immune senescence in Hodgkin lymphoma aetiology from 1992 Danish cases. [PDF]
Int J CancerWhat's New? The understanding of the epidemiological and clinical distinctions between Epstein–Barr virus (EBV)‐positive and EBV‐negative classic Hodgkin lymphoma remains incomplete. Here, the authors generated unique sets of population‐based sex‐ and age‐specific incidence rates of classic Hodgkin lymphoma in Denmark stratified by histological subtype
Rostgaard K +18 more
europepmc +2 more sources
Effects of Different Proportions of Corn Silage and Ramie Silage on In Vitro Rumen Fermentation Characteristics and Methane Production [PDF]
AnimalsThis study investigated the interactive effects of corn silage and ramie silage on in vitro rumen fermentation characteristics, aiming to provide a scientific basis and empirical evidence for the rational incorporation of ramie into ruminant diets.
Honghui Qi +3 more
doaj +2 more sources
Genetic Differentiation in the SdhC Subunit Confers Intrinsic Resistance to SDHI Fungicides in Fusarium asiaticum. [PDF]
Mol Plant PatholIn Fusarium asiaticum, two homologous SdhC subunits (FaSdhC1/C2) regulate sensitivity to SDHI fungicides: deletion of FaSDHC1 decreases sensitivity, while deletion of FaSDHC2 increases it. Multiple mutations in ΔFaSDHC2 confer resistance to SDHI fungicides.
Song J +8 more
europepmc +2 more sources
Fermented rice polishings dietary supplementation sustainably enhanced growth performance, gut morphology, immune response and antioxidant status of Nile tilapia [PDF]
Scientific ReportsFermentation of plant-derived by-products, including rice polishings (RP), is suggested for the sustainability of the aquafeed industry. In this study, fermented rice polishings (FRP) were incorporated into Nile tilapia diets at various levels: 0, 100 ...
Amr Ismail Zaineldin +4 more
doaj +2 more sources
Less workplace parking with fully autonomous vehicles? [PDF]
Journal of Intelligent and Connected Vehicles, 2022 Purpose – Recent studies on commuter parking in an age of fully autonomous vehicles (FAVs) suggest, that the number of parking spaces close to the workplace demanded by commuters will decline because of the capability of FAVs to return home, to seek out (
Stefan Tscharaktschiew, Felix Reimann
doaj +1 more source
Apical root canal cleaning after preparation with endodontic instruments: a randomized trial in vivo analysis [PDF]
Restorative Dentistry & Endodontics, 2020 ObjectivesThis study aimed to evaluate vital pulp tissue removal from different endodontic instrumentation systems from root canal apical third in vivo.Materials and MethodsThirty mandibular molars were selected and randomly divided into 2 test groups ...
Volmir João Fornari +6 more
doaj +1 more source
Managing Supply Chains During the Covid-19 Pandemic
Central European Management Journal, 2022 Purpose: The Covid-19 pandemic disrupted the lives of people and organizations, including supply chains (SC). Therefore, this study aims to explore concepts, methods, and tools for managing SC during the Covid-19 pandemic.
Mańkowski Cezary +2 more
doaj +1 more source