Results 1 to 10 of about 60 (54)

A single amino acid substitution (R441A) in the receptor-binding domain of SARS coronavirus spike protein disrupts the antigenic structure and binding activity [PDF]

Biochemical and Biophysical Research Communications, 2006
The spike (S) protein of severe acute respiratory syndrome coronavirus (SARS-CoV) has two major functions: interacting with the receptor to mediate virus entry and inducing protective immunity. Coincidently, the receptor-binding domain (RBD, residues 318-510) of SAR-CoV S protein is a major antigenic site to induce neutralizing antibodies.
He, Yuxian, Li, Jingjing, Jiang, Shibo
europepmc   +6 more sources

FBXO7 Confers Mesenchymal Properties and Chemoresistance in Glioblastoma by Controlling Rbfox2-Mediated Alternative Splicing. [PDF]

Adv Sci (Weinh), 2023
Li S, Chen Y, Xie Y, Zhan H, Zeng Y, Zeng K, Wang L, Zhan Z, Li C, Zhao L, Chen X, Tan Y, Wang Z, Bu J, Song Y, Deng F, Zhou A.   +16 more
europepmc   +1 more source

Depending on Epitope Profile of COVID-19 mRNA Vaccine Recipients: Are They More Efficient Against the Arising Viral Variants? An Opinion Article. [PDF]

Front Med (Lausanne), 2022
Abd El-Baky N, Amara AAAF.
europepmc   +1 more source

ORC1 binds to cis-transcribed RNAs for efficient activation of replication origins. [PDF]

Nat Commun, 2023
Mas AM, Goñi E, Ruiz de Los Mozos I, Arcas A, Statello L, González J, Blázquez L, Lee WTC, Gupta D, Sejas Á, Hoshina S, Armaos A, Tartaglia GG, Waga S, Ule J, Rothenberg E, Gómez M, Huarte M.   +17 more
europepmc   +1 more source

Biosensors for Point Mutation Detection. [PDF]

Front Bioeng Biotechnol, 2021
Jiang H, Xi H, Juhas M, Zhang Y.
europepmc   +1 more source

COVID-19 susceptibility: potential of <i>ACE2</i> polymorphisms. [PDF]

Egypt J Med Hum Genet, 2020
Chaudhary M.
europepmc   +1 more source

A non-translational role of threonyl-tRNA synthetase in regulating JNK signaling during myogenic differentiation. [PDF]

FASEB J, 2021
Dai C, Reyes-Ordoñez A, You JS, Chen J.
europepmc   +1 more source

Cryo-EM structure of C9ORF72-SMCR8-WDR41 reveals the role as a GAP for Rab8a and Rab11a. [PDF]

Proc Natl Acad Sci U S A, 2020
Tang D, Sheng J, Xu L, Zhan X, Liu J, Jiang H, Shu X, Liu X, Zhang T, Jiang L, Zhou C, Li W, Cheng W, Li Z, Wang K, Lu K, Yan C, Qi S.   +17 more
europepmc   +1 more source

Epitope Profiling Reveals the Critical Antigenic Determinants in SARS-CoV-2 RBD-Based Antigen. [PDF]

Front Immunol, 2021
Jiang M, Zhang G, Liu H, Ding P, Liu Y, Tian Y, Wang Y, Wang A.   +7 more
europepmc   +1 more source

A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic viruses. [PDF]

Nat Commun, 2021
Hardy JM, Newton ND, Modhiran N, Scott CAP, Venugopal H, Vet LJ, Young PR, Hall RA, Hobson-Peters J, Coulibaly F, Watterson D.   +10 more
europepmc   +1 more source