The R&D/marketing interface in product innovation : a case of the UK pharmaceutical industry [PDF]
This R&D/marketing interface study is of a multi-disciplinary nature. In the study the role of the R&D/marketing interface is re arded as the pursuit of competitive advantage through negotiated exchange process between the two parties.
Wang, Qing
core
Kienbock's Disease in a Young Female without Classical Risk Factors: A Case Report with 1-year Functional Outcome Following Proximal Row Carpectomy. [PDF]
J Orthop Case RepKarthikeyan RKS +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Rina Sa,1 Jingjing Zhang,1 Haiyang Xu2 1Department of Ophthalmology, The First Hospital of Jilin University, Changchun, People’s Republic of China; 2Department of Anesthesia, The First Hospital of Jilin University, Changchun, People’s Republic of ...
Zhang J, Sa R, Xu H
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Superficial Fungal Infection Associations with Comorbid Diseases and Risk Factors: An Analysis of Global Burden of Disease 2023. [PDF]
Infect Dis RepGupta AK, Teasell E, Economopoulos V.
europepmc +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Critical Success Factors for a Knowledge-Based Economy: An Empirical Study into Background Factors of Economic Dynamism [PDF]
The past decade has shown a rising popularity of the notion of the knowledge-based economy. In Europe this has led to important political paradigms such as the Lisbon Accord and the Barcelona targets, which have become signposts for R&D policy in the EU.
Van Hemert, Patricia, Nijkamp, Peter
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The Volume and Density of Epicardial Adipose Tissue Measured by Computed Tomography as Markers of the Effects of Cardiovascular Disease Risk Factors. [PDF]
J Cardiovasc Dev DisGać P, Cheładze P, Poręba R.
europepmc +1 more source
Fertility Inhibition of an N Group R Factor by a Group X R Factor, R6K [PDF]
Journal of General Microbiology, 1974 R J, Pinney, J T, Smith
openaire +2 more sources