Results 11 to 20 of about 3,332,671 (263)

Precision medicine: an approach to R&D for delivering superior medicines to patients [PDF]

open access: yesClinical and Translational Medicine, 2012
AbstractPharmaceutical R&D productivity has declined over the last decade despite increasing investments. Recent trends, however, indicate a potential reversal of this trend fueled by a wave of new biologics, vaccines and highly selective NCEs directed against targets validated by human genetics, focus on new disease areas including orphan and ...
Mikael Dolsten, Morten Søgaard
openaire   +3 more sources

EUPATI Guidance for Patient Involvement in Medicines Research and Development (R&D); Guidance for Pharmaceutical Industry-Led Medicines R&D [PDF]

open access: yesFrontiers in Medicine, 2018
The importance and merits of greater patient involvement in medicines research and development (R&D) are commonly acknowledged and are thought to offer benefits for all involved parties. It helps to improve discovery, development, and evaluation of new effective medicines, based on the collaborative identification and understanding of unmet needs ...
Warner   +6 more
openaire   +3 more sources

Cancer patients' attitudes towards Chinese medicine: a Hong Kong survey

open access: yesChinese Medicine, 2009
Background This article reports a survey conducted in Hong Kong on the cancer patients' attitudes towards Chinese medicine treatment. Methods Cancer patients from three Chinese medicine clinics and one oncology clinic were interviewed with a structured ...
Law Chun-key   +5 more
doaj   +1 more source

Contributions of body fat, fat free mass and arm muscle area in athletic performance of wheelchair basketball players

open access: yesMotricidade, 2017
The aims of this study were: to verify the relationship (1) and dependency (2) between body fat (BF), fat free mass (FFM) and the arm muscle area (AMA) with athletic performance of wheelchair basketball players.
Lúcia Oliveira   +3 more
doaj   +1 more source

A novel automated SARS-CoV-2 saliva PCR test protects a global asymptomatic workforce

open access: yesScientific Reports, 2021
Regular PCR testing of nasopharyngeal swabs from symptomatic individuals for SARS-CoV-2 virus has become the established method by which health services are managing the COVID-19 pandemic.
Nikki Carter   +17 more
doaj   +1 more source

Material Stiffness in Cooperation with Macrophage Paracrine Signals Determines the Tenogenic Differentiation of Mesenchymal Stem Cells

open access: yesAdvanced Science, 2023
Stiffness is an important physical property of biomaterials that determines stem cell fate. Guiding stem cell differentiation via stiffness modulation has been considered in tissue engineering. However, the mechanism by which material stiffness regulates
Renwang Sheng   +16 more
doaj   +1 more source

GMIEC: a shiny application for the identification of gene-targeted drugs for precision medicine

open access: yesBMC Genomics, 2020
Background Precision medicine is a medical approach that takes into account individual genetic variability and often requires Next Generation Sequencing data in order to predict new treatments.
Guidantonio Malagoli Tagliazucchi   +1 more
doaj   +1 more source

Matt R. Anderson and the Social Medicine Journal

open access: yesSocial Medicine
Matt Anderson is an exceptional person, and  without a doubt, throughout his broad and diverse professional career, one of his greatest  contributions was the creation of the Social Medicine Journal  and, through his personal commitment and drive ...
Florencia Peña   +2 more
doaj   +1 more source

Nutritional Status and its Associated Factors Among Under-Five Children Attending the Well Baby Clinic of a Tertiary Care Institute of Kolkata, India [PDF]

open access: yesHealthline
Introduction: A Well-Baby Clinic (WBC) is a primary healthcare facility, where children are monitored for growth and development, receive routine immunization and their caregivers are given appropriate nutritional counselling.
Somnath Naskar   +5 more
doaj   +1 more source

Usability of deep learning and H&E images predict disease outcome-emerging tool to optimize clinical trials

open access: yesnpj Precision Oncology, 2022
Understanding factors that impact prognosis for cancer patients have high clinical relevance for treatment decisions and monitoring of the disease outcome.
Talha Qaiser   +7 more
doaj   +1 more source

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