Results 71 to 80 of about 1,832,641 (315)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Development of Physics Applied to Medicine in the UK, 1945–90
, 2006 Annotated and edited transcript of a Witness Seminar held on 5 July 2005. Introduction by Dr Jeff Hughes.First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2006.©The Trustee of the Wellcome Trust, London, 2006.All volumes ...
Christie, DA, Tansey, EM
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A Delphi developed syllabus for the medical specialty of sport and exercise medicine.
, 2018 Training in the medical specialty of sport and exercise medicine is now available in many, but not all countries. Lack of resources may be a barrier to the development of this important specialty field and the International Syllabus in Sport and Exercise
Jaques, R. +2 more
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Heart Rate Variability Analysis in General Medicine [PDF]
, 2003 Autonomic nervous system plays an integral role in homeostasis. Autonomic modulation can frequently be altered in patients with cardiac disorders as well as in patients with other critical illnesses or injuries.
Marek Malik +5 more
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Role of proinflammatory biomarkers in Parkinson's disease with non-motor symptoms: A systematic review and meta-analysis [PDF]
Romanian Journal of NeurologyBackground and objectives. Neuroinflammation, characterized by microglial activation and elevated proinflammatory cytokines, plays a crucial role in Parkinson's disease (PD) pathogenesis and is linked to neurodegeneration and non-motor symptoms.
Setiawan Sulisthio +2 more
doaj +1 more source
, 2008 Title from Web page (viewed Oct. 7, 2008).; "September 18, 2008."; Discusses what evidence-based medicine is; who determines when medicine is evidence-based; how these decisions are translated into medical practice and health policy; obstacles health ...
Spigel, Saul.
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, 2000 It's a current belief that stress is an outstanding feature of intensive care units, in particular within nursing staff. The aim of this study was to compare some variables belonging to stress (i.e.
M. Malacrida +6 more
core +1 more source
Preregistration house officers in general practice: review of evidence [PDF]
, 2003 OBJECTIVES: To examine the strengths and weaknesses of the national and local schemes for preregistration house officers to spend four months in general practice, to identify any added value from such placements, and to examine the impact on career ...
O'Halloran, C. +7 more
core +1 more source