Results 51 to 60 of about 10,014,798 (291)

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Pediatric Oncology Nursing Competencies in Latin America and the Caribbean: A Scoping Review to Inform Practice, Education, and Research

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior   +7 more
wiley   +1 more source

Mesenchymal stem cell-derived exosome subpopulations remained consistent for 28 culture days, displaying therapeutic effects in a silicosis mouse model

open access: yesFrontiers in Cell and Developmental Biology
IntroductionThe clinical translation of mesenchymal stem cell-derived exosome faces critical challenges in scalable production, subpopulation stability, and therapeutic route optimization.
Lina Zhang   +18 more
doaj   +1 more source

Developing (r,Q) & (R,T) inventory control models [PDF]

open access: yesMuṭāli̒āt-i Mudīriyyat-i Ṣan̒atī, 2014
In this paper we have developed inventory control models (r,Q) & (R,T) in multi-items environment by two objectives as minimizing costs (holding & shortage) and risk level under four constraints. These constraints include: available budge, service level,
Magsud Amiri   +2 more
doaj  

Cognitive Diagnosis Models in R: A didactic [PDF]

open access: yesTutorials in Quantitative Methods for Psychology, 2015
Cognitive diagnosis models (CDMs) are a class of discrete latent variable modelswhich may be used to estimate the possession of attributes underlying a global ability or attitude.
George, A. C., Robitzsch, A.
doaj   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel   +3 more
wiley   +1 more source

Neutrino masses in R-parity violating supersymmetric models

open access: yes, 2003
We study neutrino masses and mixing in R-parity violating supersymmetric models with generic soft supersymmetry breaking terms. Neutrinos acquire masses from various sources: Tree level neutrino--neutralino mixing and loop effects proportional to ...
A. Abada   +77 more
core   +1 more source

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash   +4 more
wiley   +1 more source

Are f(R) dark energy models cosmologically viable ?

open access: yes, 2007
All $f(R)$ modified gravity theories are conformally identical to models of quintessence in which matter is coupled to dark energy with a strong coupling. This coupling induces a cosmological evolution radically different from standard cosmology. We find
David Polarski   +3 more
core   +3 more sources

Prevalence and Trajectory of Household Material Hardship Among Children With Advanced Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Families of children with advanced cancer living in poverty experience inferior outcomes including poor parent mental health and worse child quality of life. Household material hardship (HMH: food, housing, transportation, and/or utility insecurity) is a modifiable poverty exposure—and potential intervention target—that ...
Sarah Wright   +13 more
wiley   +1 more source

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