Results 131 to 140 of about 19,195,534 (303)

The translator of Petri-object model visual programming language

open access: yes, 2022
High-level programming tools are aimed at increasing the development speed of complex programs due to automation within the routine actions of the programmer, reducing the number of coding errors and reducing the code in general.
Dyfuchyn, А.Yu.
core  

On constraint qualifications in mathematical programming

open access: yesДоклады Белорусского государственного университета информатики и радиоэлектроники, 2019
The article is devoted to the condition of R-regularity (Error Bound Property) in problems of mathematical programming. This condition plays an important role in analyzing the convergence of numerical optimization algorithms and it is a fairly general ...
L. I. Minchenko, S. I. Sirotko
doaj  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

RGtk2: A Graphical User Interface Toolkit for R [PDF]

open access: yes
Graphical user interfaces (GUIs) are growing in popularity as a complement or alternative to the traditional command line interfaces to R. RGtk2 is an R package for creating GUIs in R.
Duncan Temple Lang, Michael Lawrence
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

SCIOER Course : C Programming

open access: yes, 2023
This project is made possible with funding by the Government of Ontario and through eCampusOntario’s support of the Virtual Learning Strategy. To learn more about the Virtual Learning Strategy visit: https://vls.ecampusontario.ca.This resource is part of
Asch, Marshall   +2 more
core  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Multiple Objective Programming Involving Differentiable (Hp, r)-invex Functions

open access: yesCubo, 2011
In this paper, we introduce new types of generalized convex functions which include locally (Hp, r)-pre-invex functions and (Hp, r)-invex functions. Relationship between these two new classes of functions are established.
Xiaoling Liu   +4 more
doaj  

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