Results 171 to 180 of about 19,195,534 (303)

Optimizing Cochlear Implant Programming in Single-Sided Deafness and Asymmetric Hearing Loss: A Randomized Comparison of ESRT and Behavioral Methods. [PDF]

Laryngoscope Investig Otolaryngol
Holcomb MA, Coto J, Sarangoulis C, Stern T, Prentiss S, Glassman EK, Smeal MR.   +6 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Modeling and solving linear programming with R

Linear programming is one of the most extensively used techniques in the toolbox of quantitative methods of optimization. One of the reasons of the popularity of linear programming is that it allows to model a large variety of situations with a simple ...
Sallán Leyes, José María, Lordan González, Oriol, Fernández Alarcón, Vicenç   +2 more
core  

Inside a Programmer's Brain: Dissociating Code and Language Comprehension Networks Using a Novel fMRI-ESM Protocol. [PDF]

Hum Brain Mapp
Cepero-Escribano V, León-Cabrera P, Gasa-Roqué A, Otazu X, Fernandez-Coello A, Naval-Baudin P, Camins À, Rico I, Gabarros A, Rodriguez-Fornells A, Cerda-Company X.   +10 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Building a Rural, Coalition-Based Approach to Youth Substance Use Prevention: The Drug Free Dickson Coalition Model. [PDF]

J Public Health Manag Pract
Thompson KR.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Using R Programming in a Financial Derivatives Course

R is a popular and free programming language and software environment for statistical computing and graphics. We use a class project in an undergraduate financial derivatives course to introduce students to R programming. Specifically, through pricing

core  

Adaptive dual-programming magnetic soft robot with lifelike behavior. [PDF]

Sci Adv
Ye Y, Xu C, Wang S, Li W, Wu R, Wu H, Xia N, Yang T, Song S, Zhang L, Dong Y, Li B.   +11 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source