Results 41 to 50 of about 8,226,807 (254)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

High-Dimensional Inference: Confidence Intervals, $p$-Values and R-Software hdi

open access: yes, 2015
We present a (selective) review of recent frequentist high-dimensional inference methods for constructing $p$-values and confidence intervals in linear and generalized linear models.
Bühlmann, Peter   +3 more
core   +1 more source

Getting Started with Particle Metropolis-Hastings for Inference in Nonlinear Dynamical Models [PDF]

open access: yes, 2019
This tutorial provides a gentle introduction to the particle Metropolis-Hastings (PMH) algorithm for parameter inference in nonlinear state-space models together with a software implementation in the statistical programming language R.
Dahlin, Johan, Schön, Thomas B.
core   +3 more sources

Defining Roles in Pediatric Palliative Care: Perspectives From Oncology and Palliative Care Teams

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Early integration of pediatric palliative care (PPC) is associated with improved symptom management, quality of life, and healthcare utilization for children with cancer. Despite this, variation persists in how PPC is understood, operationalized, and integrated within pediatric oncology programs. In particular, ambiguity surrounding
Leeat Granek   +13 more
wiley   +1 more source

Multi-category diagnostic accuracy based on logistic regression

open access: yesStatistical Theory and Related Fields, 2017
We provide a detailed review for the statistical analysis of diagnostic accuracy in a multi-category classification task. For qualitative response variables with more than two categories, many traditional accuracy measures such as sensitivity ...
Jialiang Li   +2 more
doaj   +1 more source

On the number of perfect matchings in random polygonal chains

open access: yesOpen Mathematics, 2023
Let GG be a graph. A perfect matching of GG is a regular spanning subgraph of degree one. Enumeration of perfect matchings of a (molecule) graph is interest in chemistry, physics, and mathematics.
Wei Shouliu   +3 more
doaj   +1 more source

Design and implementation of shoes arrangement robot system for unknown environment

open access: yesShenzhen Daxue xuebao. Ligong ban, 2022
In recent years, the robot and artificial intelligence technology have developed rapidly, but there still remains a challenging problem to realize the contact operation of robot in home environment. In order to make the robot arrange shoes automatically,
TANG Xiaolong, HUANG Hui
doaj   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Generative adversarial network for low‐light image enhancement

open access: yesIET Image Processing, 2021
Low‐light image enhancement is rapidly gaining research attention due to the increasing demands of extreme visual tasks in various applications. Although numerous methods exist to enhance image qualities in low light, it is still undetermined how to ...
Fei Li   +2 more
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

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