Results 31 to 40 of about 20,570 (99)

Gene expression profiling after exposure to a chemical carcinogen, Pentabrominated Diphenyl Ether, at different life stages

Frontiers in Toxicology, 2023
Exposure to environmental hazards occurs at different stages of our lifetime–infant, child, adult. This study integrates recently published toxicogenomics data to examine how exposure to a known rat chemical carcinogen (pentabrominated diphenyl ether ...
Keith R. Shockley, June K. Dunnick
doaj   +1 more source

Silver nanoparticle interactions with glycated and non-glycated human serum albumin mediate toxicity

Frontiers in Toxicology, 2023
Introduction: Biomolecules bind to and transform nanoparticles, mediating their fate in biological systems. Despite over a decade of research into the protein corona, the role of protein modifications in mediating their interaction with nanomaterials ...
Hee-Yon Park, Christopher Chung, Madeline K. Eiken, Karl V. Baumgartner, Kira M. Fahy, Kaitlyn Q. Leung, Evangelia Bouzos, Prashanth Asuri, Korin E. Wheeler, Kathryn R. Riley   +9 more
doaj   +1 more source

The application of natural language processing for the extraction of mechanistic information in toxicology

Frontiers in Toxicology
To study the ways in which compounds can induce adverse effects, toxicologists have been constructing Adverse Outcome Pathways (AOPs). An AOP can be considered as a pragmatic tool to capture and visualize mechanisms underlying different types of toxicity
Marie Corradi, Thomas Luechtefeld, Thomas Luechtefeld, Alyanne M. de Haan, Raymond Pieters, Raymond Pieters, Jonathan H. Freedman, Tamara Vanhaecke, Mathieu Vinken, Marc Teunis   +9 more
doaj   +1 more source

British business cycles, 1270–1870

Cliometrica
Annual estimates of GDP constructed from the output side are used to analyse British business cycles between 1270 and 1870. After c.1670, the scale of recessions tended to diminish as the economy grew, diversified and became more resilient. Until c.1730,
Stephen Broadberry, Bruce M. S. Campbell, Alexander Klein, M. Overton, Bas van Leeuwen   +4 more
semanticscholar   +1 more source

Depleting circ_0088364 restrained cell growth and motility of human hepatocellular carcinoma via circ_0088364-miR-1270-COL4A1 ceRNA pathway

Cell Cycle, 2021
Circular RNA hsa_circ_0088364 (circ_0088364) is a contributory factor in the malignancy of hepatocellular carcinoma (HCC). We aimed to elaborate its role and competing endogenous RNA (ceRNA) mechanism in HCC cell growth and motility.
K. Sun, Hao Wang, Dongyuan Zhang, Yupeng Li, Lei Ren   +4 more
semanticscholar   +1 more source

Developing a pragmatic consensus procedure supporting the ICH S1B(R1) weight of evidence carcinogenicity assessment

Frontiers in Toxicology
The ICH S1B carcinogenicity global testing guideline has been recently revised with a novel addendum that describes a comprehensive integrated Weight of Evidence (WoE) approach to determine the need for a 2-year rat carcinogenicity study.
Arianna Bassan, Ronald Steigerwalt, Douglas Keller, Lisa Beilke, Paul M. Bradley, Frank Bringezu, William J. Brock, Leigh Ann Burns-Naas, Jon Chambers, Kevin Cross, Michael Dorato, Rosalie Elespuru, Douglas Fuhrer, Frances Hall, Jim Hartke, Gloria D. Jahnke, Felix M. Kluxen, Eric McDuffie, Friedemann Schmidt, Jean-Pierre Valentin, David Woolley, Doris Zane, Glenn J. Myatt   +22 more
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Observation of D^{0}→K_{1}(1270)^{-}e^{+}ν_{e}.

Physical Review Letters, 2021
Using 2.93  fb^{-1} of e^{+}e^{-} collision data taken with the BESIII detector at a center-of-mass energy of 3.773 GeV, the observation of the D^{0}→K_{1}(1270)^{-}e^{+}ν_{e} semileptonic decay is presented.
B. C. M. Ablikim, M. Achasov, P. Adlarson, S. Ahmed, M. Albrecht, R. Aliberti, A. Amoroso, M. An, Q. An, X. Bai, Y. Bai, O. Bakina, R. Ferroli, I. Balossino, Y. Ban, K. Begzsuren, N. Berger, M. Bertani, D. Bettoni, F. Bianchi, J. Bloms, A. Bortone, I. Boyko, R. Briere, H. Cai, X. Cai, A. Calcaterra, G. Cao, N. Cao, S. Cetin, J. Chang, W. Chang, G. Chelkov, D. Chen, G. Chen, H. Chen, M. Chen, S. Chen, X. Chen, Y. Chen, Z. Chen, W. Cheng, G. Cibinetto, F. Cossio, X. Cui, H. Dai, X. Dai, A. Dbeyssi, R. Boer, D. Dedovich, Z. Deng, A. Denig, I. Denysenko, M. Destefanis, F. DeMori, Y. Ding, C. Dong, J. Dong, L. Dong, M. Dong, X. Dong, S. Du, Y. Fan, J. Fang, S. Fang, Y. Fang, R. Farinelli, L. Fava, F. Feldbauer, G. Felici, C. Feng, J. Feng, M. Fritsch, C. Fu, Y. Gao, Y. Gao, I. Garzia, P. Ge, C. Geng, E. Gersabeck, A. Gilman, K. Goetzen, L. Gong, W. Gong, W. Gradl, M. Greco, L. Gu, M. Gu, S. Gu, Y. T. Gu, C. Guan, A. Guo, L. Guo, R. Guo, Y. Guo, A. Guskov, T. Han, W. Han, X. Hao, F. Harris, K. He, F. Heinsius, C. H. Heinz, T. Held, Y. Heng, C. Herold, M. Himmelreich, T. Holtmann, G. Hou, Y. Hou, Z. Hou, H. Hu, J. F. Hu, T. Hu, Y. Hu, G. Huang, L. Huang, X. T. Huang, Y. Huang, Z. Huang, T. Hussain, N. Husken, W. Andersson, W. Imoehl, M. Irshad, S. Jaeger, S. Janchiv, Q. Ji, Q. Ji, X. Ji, X. Ji, Y. Ji, H. Jiang, X. Jiang, J. Jiao, Z. Jiao, S. Jin, Y. Jin, M. Jing, T. Johansson, N. Kalantar-Nayestanaki, X. Kang, R. Kappert, M. Kavatsyuk, B. Ke, I. Keshk, A. Khoukaz, P. Kiese, R. Kiuchi, R. Kliemt, L. Koch, O. B. Kolcu, B. Kopf, M. Kuemmel, M. Kuessner, A. Kupsc, M. Kurth, W. Kuhn, J. J. Lane, J. Lange, P. Larin, A. Lavania, L. Lavezzi, Z. Lei, H. Leithoff, M. Lellmann, T. Lenz, C. Li, C. Li, Cheng Li, D. Li, F. Li, G. Li, H. Li, H. Li, H. J. Li, J. Li, J. Li, J. Li, Kenneth K. Li, L. Li, Lei Li, P. R. Li, S. Li, W. Li, W. Li, X. Li, X. Li, Xiaoyu Li, Z. Li, H. Liang, Y. Liang, Y. Liang, G. Liao, L. Liao, J. Libby, C. X. Lin, B. Liu, C. Liu, D. Liu, F. Liu, Fang Liu, Feng. Liu, H. Liu, H. Liu, Huanhuan Liu, Huihui Liu, J. Liu, J. Liu, J. Liu, Li-Yu Daisy Liu, Li-Yu Daisy Liu, Li-Yu Daisy Liu, M. Liu, Li-Yu Daisy Liu, Q. Liu, S. Liu, Shuai Liu, T. Liu, W. Liu, X. Liu, Y. Liu, Y. Liu, Z. Liu, Z. Liu, X. Lou, F. Lu, H. J. Lu, J. Lu, J. Lu, X. Lu, Y. Lu, Y. Lu, C. Luo, M. Luo, P. Luo, T. Luo, X. Luo, S. Lusso, X. Lyu, F. Ma, H. Ma, L. Ma, M. Ma, Q. Ma, R. Ma, R. Ma, X. Ma, X. Ma, F. Maas, M. Maggiora, S. Maldaner, S. Malde, A. Mangoni, Y. Mao, Z. Mao, S. Marcello, Z. Meng, J. Messchendorp, G. Mezzadri, T. Min, R. Mitchell, X. Mo, Y. Mo, N. Muchnoi, H. Muramatsu, S. Nakhoul, Y. Nefedov, F. Nerling, I. Nikolaev, Z. Ning, S. Nisar, S. Olsen, Q. Ouyang, S. Pacetti, X. Pan, Y. Pan, A. Pathak, P. Patteri, M. Pelizaeus, H. Peng, K. Peters, J. Pettersson, J. Ping, R. Ping, R. Poling, V. Prasad, H. Qi, H. Qi, K. Qi, M. Qi, T. Qi, S. Qian, W. Qian, Z. Qian, C. Qiao, L. Qin, X. Qin, X. Qin, Z. Qin, J. Qiu, S. Qu, K. H. Rashid, K. Ravindran, C. Redmer, A. Rivetti, V. Rodin, M. Rolo, G. Rong, C. Rosner, M. Rump, H. Sang, A. Sarantsev, Y. Schelhaas, C. Schnier, K. Schoenning, M. Scodeggio, D. Shan, W. Shan, X. Shan, J. F. Shangguan, M. Shao, C. Shen, H. Shen, P. Shen, X. Shen, H. Shi, R. Shi, X. Shi, X. Shi, J. Song, W. Song, Y. Song, S. Sosio, S. Spataro, K. Su, P. Su, F. Sui, G. Sun, H. Sun, J. F. Sun, L. Sun, S. Sun, T. Sun, W. Sun, X. Sun, Y. Sun, Y. K. Sun, Y. Z. Sun, Z. Sun, Y. Tan, Y. Tan, C. Tang, G. Tang, J. Tang, J. Teng, V. Thorén, W. Tian, Y. Tian, I. Uman, B. Wang, C. W. Wang, D. Wang, H. Wang, H. Wang, K. Wang, L. Wang, M. Wang, M. Wang, Meng Wang, W. Wang, W. Wang, W. Wang, X. Wang, X. Wang, X. Wang, Y. Wang, Y. Wang, Y. F. Wang, Y. Wang, Y. Wang, Z. Wang, Z. Wang, Ziyi Wang, Zongyuan Wang, D. Wei, P. Weidenkaff, F. Weidner, S. Wen, D. White, U. Wiedner, G. Wilkinson, M. Wolke, L. Wollenberg, J. Wu, L. Wu, L. Wu, X. Wu, Z. Wu, L. Xia, H. Xiao, S. Xiao, Z. Xiao, X. Xie, Y. Xie, Y. Xie, T. Xing, G. Xu, Q. Xu, W. Xu, X. Xu, Y. Xu, F. Yan, L. Yan, W. Yan, W. Yan, Xueqing Yan, H. Yang, H. Yang, L. Yang, S. Yang, Y. Yang, Yifan Yang, Zhi Yang, M. Ye, M. Ye, J. Yin, Z. You, B. Yu, C. Yu, G. Yu, J. Yu, T. Yu, C. Yuan, L. Yuan, X. Yuan, Y. Yuan, Z. Yuan, C. Yue, A. Yuncu, A. Zafar, Zeng, Y. Zeng, A. Zhang, B. Zhang, Guangyi Zhang, H. Zhang, H. H. Zhang, H. Y. Zhang, J. Zhang, J. Zhang, J. Zhang, J. W. Zhang, J. Y. Zhang, J. Z. Zhang, Jianyu Zhang, Jiawei Zhang, L. Zhang, L. Zhang, Lei Zhang, S. Zhang, S. Zhang, Shulei Zhang, X. D. Zhang, X. Y. Zhang, Y. Zhang, Y. H. Zhang, Y. Zhang, Yan Zhang, Yao Zhang, Y. Zhang, Z. Zhang, Z. Zhang, G. Zhao, J. Zhao, J. Zhao, J. Zhao, Lei Zhao, Ling Zhao, M. Zhao, Q. Zhao, S. Zhao, Y. B. Zhao, Y. Zhao, Z. Zhao, A. Zhemchugov, B. Zheng, J. Zheng, Y. Zheng, Y. Zheng, B. Zhong, C. Zhong, L. Zhou, Q. Zhou, X. Zhou, X. Zhou, X. Zhou, X. Zhou, A. Zhu, J. Zhu   +499 more
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Respectable standards of living: The alternative lens of maintenance costs, Britain 1270–1860

The Economic History Review
This paper argues that in all societies there is considerable agreement about what goods and services are needed to provide a decent living, and that this standard can be measured by the expense involved in maintaining people of good standing ...
Jane Humphries
semanticscholar   +1 more source

Insight on cytotoxic NHC gold(I) halide complexes evaluated in multifaceted culture systems

Current Research in Toxicology
Gold complexes can be a useful system in the fight against cancer. Although many studies have been carried out on in vitro 2D cell culture models embryotoxic assays are particularly lacking.
Vincenza De Gregorio, Alessandra La Pietra, Andrea Candela, Carlo Oliviero, Ida Ferrandino, Diego Tesauro   +5 more
doaj   +1 more source

Hsa_circ_0043532 contributes to PCOS through upregulation of CYP19A1 by acting as a ceRNA for hsa-miR-1270

Journal of Ovarian Research
Polycystic ovarian syndrome (PCOS) accounts for about 75% of anovulatory infertility. The cause of PCOS is not clear. CircRNAs acting as miRNA sponges mediate the post-transcriptional regulation of multiple genes.
Huimin Zhang, Jianye Fang, Yingxue Liu, Wenqian Zhu, Yang Xu, Yu Zhang, Wei Shen, Duan Li, Cuifang Hao   +8 more
semanticscholar   +1 more source