Nucleolin mediates the internalization of rabbit hemorrhagic disease virus through clathrin-dependent endocytosis. [PDF]
Rabbit hemorrhagic disease virus (RHDV) is an important member of the Caliciviridae family and a highly lethal pathogen in rabbits. Although the cell receptor of RHDV has been identified, the mechanism underlying RHDV internalization remains unknown.
Jie Zhu +8 more
doaj +1 more source
New variant of rabbit hemorrhagic disease virus, Portugal, 2012-2013 [PDF]
The Portuguese Foundation for Science and Technology supported the doctoral fellowship of A.M.L. (SFRH/BD/78738/2011) and the postdoctoral fellowship of J.A. (SFRH/ BPD/73512/2010).
Abrantes, Joana +8 more
core +1 more source
Introduction. Rabbit hemorrhagic disease is an acute highly contagious infection associated with two genotypes of pathogenic Lagovirus. Antibodies to major capsid protein (Vp60) are protective.
Aleksey N. Mukhin +6 more
doaj +1 more source
Tracking the Origin of a Rabbit Haemorrhagic Virus 2 Outbreak in a Wild Rabbit Breeding Centre in Portugal; Epidemiological and Genetic Investigation [PDF]
As key prey, the wild rabbit downsize constitutes a major drawback on the endangered Iberian lynx (Lynx pardinus) re-introduction in the Iberia. Several captive breeding units mostly located in Alentejo, endeavour the wild rabbit repopulation of depleted
Barros, Sílvia +12 more
core +1 more source
Protection of Rabbits against Rabbit Hemorrhagic Disease Virus by Immunization with the VP60 Protein Expressed in Plants with a Potyvirus-Based Vector [PDF]
A new plum pox potyvirus (PPV)-based vector has been constructed for the expression of full-length individual foreign proteins. The foreign sequences are cloned between the NIb replicase and capsid protein (CP) cistrons. The heterologous protein is split
Fernández-Fernández, María Rosario +5 more
core +2 more sources
Immunity against Lagovirus europaeus and the Impact of the Immunological Studies on Vaccination
In the early 1980s, a highly contagious viral hemorrhagic fever in rabbits (Oryctolagus cuniculus) emerged, causing a very high rate of mortality in these animals.
Claudia Müller +6 more
doaj +1 more source
Cardiotrophin-1 promotes a high survival rate in rabbits with lethal fulminant hepatitis of viral origin [PDF]
Rabbit hemorrhagic disease virus (RHDV) causes lethal fulminant hepatitis closely resembling acute liver failure (ALF) in humans. In this study, we investigated whether cardiotrophin-1 (CT-1), a cytokine with hepatoprotective properties, could attenuate ...
Alvarez, M. (Marcelino) +9 more
core +2 more sources
Rabbit Hemorrhagic Disease Virus Non-structural Protein 6 Induces Apoptosis in Rabbit Kidney Cells
Rabbit hemorrhagic disease (RHD) is a highly contagious disease caused by rabbit hemorrhagic disease virus (RHDV). Previous research has shown that RHDV induces apoptosis in numerous cell types, although the molecular mechanisms underlying the apoptosis ...
Mengmeng Chen +9 more
doaj +1 more source
Confirmation of the Rabbit Hemorrhagic Disease Virus Type 2 (GI.2) Circulation in North Africa
Rabbit hemorrhagic disease (RHD) is a highly contagious viral disease that causes fatal acute hepatitis in domestic and wild lagomorphs. It has taken on major economic importance in countries like Morocco.
Saidi Aissa, Aboutaib Abdelouahed
doaj +1 more source
Objective: Rabbit viral hemorrhagic disease (VHD) is a transmittable and lethal viral illness of rabbits. In this study, genetic identification and genetic analysis of the rabbit hemorrhagic disease virus (RHDV) was made in three governorates in Egypt ...
Hanaa Awad El-Samadony +3 more
doaj +1 more source

