Results 151 to 160 of about 1,426,128 (326)

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

open access: yesFEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Nutrition of cruciate ligament reconstruction by diffusion: Collagen synthesis studied in rabbits [PDF]

open access: bronze, 1986
David Amiel   +4 more
openalex   +1 more source

Leveraging Artificial Intelligence in Research and Scholarly Work: Innovative Approaches and Practical Applications

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This article explores how artificial intelligence (AI) is reshaping scholarly research and writing for faculty in higher education. As AI becomes increasingly integrated into academic workflows, it offers opportunities to enhance efficiency, exchange ideas, and foster creativity, while also raising critical questions about authorship ...
Adam L. McClain, Scott Barton
wiley   +1 more source

Reduced Arrhythmia Inducibility With Calcium/Calmodulin-dependent Protein Kinase II Inhibition in Heart Failure Rabbits

open access: green, 2015
Gregory S. Hoeker   +4 more
openalex   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao   +10 more
wiley   +1 more source

Rabbit aortic aneurysm model with enlarging diameter capable of better mimicking human aortic aneurysm disease [PDF]

open access: gold, 2018
Yonghua Bi   +5 more
openalex   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Editorial: Behavior and Welfare of the Individual Within Large, Commercially-Relevant Groups

open access: yesFrontiers in Veterinary Science, 2021
Michael J. Toscano   +2 more
doaj   +1 more source

Lameness in a rabbit [PDF]

open access: yesLab Animal, 2011
Christopher J, Gibson   +1 more
openaire   +2 more sources

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