The contribution of extracellular RNA and its derived biomaterials in disease management
BMEMat, Volume 3, Issue 2, June 2025.The implications of exRNA's biological function and the structural uniqueness of RNA help establish a close connection between RNA, material, and modern medicine. Abstract The RNA found in the circular system is known as extracellular RNA (exRNA). This kind of RNA has been found to play a biological role similar to that of a messenger. They can be used
Yu Wei +8 more
wiley +1 more source
, 2013 Rabies vaccine is the most valuable tool to prevent rabies in humans and animals. Vaccines provide the best service to public health when used in concert with effective risk management assessment systems that include enhanced surveillance, reliable de-centralized diagnostic laboratories and continued education for health professionals. All modern human
Stanley A. Plotkin, Charles E. Rupprecht
openaire +4 more sources
Death from rabies: The reason being poor compliance to vaccination or it's failure
Journal of Family Medicine and Primary Care, 2020 Rabies is endemic in India and responsible for 20,000 human deaths every year. It is 100% preventable when the vaccine is taken along with proper wound care and rabies immunoglobulin administration though update continues regarding the requirement of the
Shyam Kishor Kumar +2 more
doaj +1 more source
Comparison of antibody titres between intradermal and intramuscular rabies vaccination using inactivated vaccine in cattle in Bhutan : a thesis presented in the partial fulfilment of the requirements for the degree of Master of Veterinary Science at Massey University, Palmerston North, New Zealand [PDF]
, 2018 In developing countries, the cost of vaccination limits the use of prophylactic rabies vaccination, especially in cattle. Intradermal vaccination delivers antigen directly to an area with higher number of antigen-presenting cells.
Wangmo, Karma
core
A two-step lyssavirus real-time polymerase chain reaction using degenerate primers with superior sensitivity to the fluorescent antigen test [PDF]
, 2014 A generic two-step lyssavirus real-time reverse transcriptase polymerase chain reaction (qRT-PCR), based on a nested PCR strategy, was validated for the detection of different lyssavirus species.
De Craeye, Stéphane +6 more
core +4 more sources
Advances in Cytosolic Delivery of Proteins: Approaches, Challenges, and Emerging Technologies
Chemistry &Biodiversity, Volume 22, Issue 6, June 2025.Proteins regulate almost all biological processes, and overcoming the protein's natural membrane inpermeability will provide a unique opportunity for intracellular targeting of related therapeutic proteins. Chemical modification of proteins and different types of delivery vectors can mediate intracellular transport of proteins, providing new ideas for ...
Wenyan Zhang +8 more
wiley +1 more source
Efficacy Of Lyophilized Inactivated Rabies Vaccine
Journal of Applied Veterinary Sciences, 2020 An interesting finding that emerged from the study was the difference in potency between inactivated rabies vaccines prepared in liquid and lyophilized forms.
Omaima A. A. Alshamandy +1 more
doaj +1 more source
Challenges and Prospects of Anti-Rabies Vaccines Production in Nigeria
, 2013 Rabies is one of the oldest known viral zoonosis and remains a serious public health hazard, especially in the developing countries. It is the major viral disease in humans living in the tropics, but it is enzootic worldwide.
I. Tekki, C. Nwosu, P. Okewole
semanticscholar +1 more source
Self-amplifying RNA vaccines for infectious diseases
Gene Therapy, 2020 Vaccinology is shifting toward synthetic RNA platforms which allow for rapid, scalable, and cell-free manufacturing of prophylactic and therapeutic vaccines. The simple development pipeline is based on in vitro transcription of antigen-encoding sequences
Kristie Bloom +2 more
semanticscholar +1 more source
Revolution of AAV in Drug Discovery: From Delivery System to Clinical Application
Journal of Medical Virology, Volume 97, Issue 6, June 2025.ABSTRACT Adeno‐associated virus (AAV) is a non‐enveloped DNA virus infecting a wide variety of species, tissues, and cell types, which is recognized as a safe and effective method for delivering therapeutic transgenes. AAV vector is the most popular viral gene delivery system in clinical delivery systems with unique and multiple advantages, such as ...
Ling Yin +6 more
wiley +1 more source