Results 271 to 280 of about 1,739,706 (302)
Some of the next articles are maybe not open access.
Journal of Virological Methods, 2017
Rabies virus is a notifiable pathogen that must be handled in high containment facilities where national and international guidelines apply. For the effective inactivation of rabies virus, a number of reagents were tested. Virkon S (1%) solution caused more than 4log reduction of rabies virus in culture medium supplemented with 10% foetal calf serum ...
Anthony R. Fooks +3 more
openaire +3 more sources
Rabies virus is a notifiable pathogen that must be handled in high containment facilities where national and international guidelines apply. For the effective inactivation of rabies virus, a number of reagents were tested. Virkon S (1%) solution caused more than 4log reduction of rabies virus in culture medium supplemented with 10% foetal calf serum ...
Anthony R. Fooks +3 more
openaire +3 more sources
Investigating the Rabies Virus
Nature, 1969Modern virological techniques are providing valuable information about the rabies virus and its behaviour in infected nerve tissue.
Klaus Hummeler +2 more
openaire +3 more sources
Antigenic variants of rabies virus
Comparative Immunology, Microbiology and Infectious Diseases, 1982Monoclonal antibodies directed either against the nucleocapsid or the glycoprotein of rabies virus were reacted by indirect immunofluorescence and mouse neutralization tests with vaccine strains and rabies field isolates of various origin. Major antigenic determinants allow the grouping of viruses and minor ones the differentiation of virus strains.
T J Wiktor +3 more
openaire +5 more sources
Rabies virus and the problems of rabies vaccination in man
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1976The structure of rabies virus and the importance of its glycoprotein in immunization are discussed. The improvement in vaccines for use in man, culminating in the production of the human diploid vaccine is described. Nevertheless problems remain, particularly with regard to post-exposure therapy.
Joan Crick, F. Brown
openaire +3 more sources
Mechanisms of Rabies Virus Neutralization
Virology, 1993The number of immunoglobulins necessary to neutralize rabies virus (CVS strain) was estimated using IgG and IgM monoclonal antibodies (MAb) specific to the three antigenic sites of the glycoprotein. It was estimated that below 130 IgG or 30 IgM bound per virions, infectivity was totally preserved.
Yves Gaudin +3 more
openaire +3 more sources
Targeting the Central Nervous System (CNS): A Review of Rabies Virus-Targeting Strategies.
Molecular Pharmaceutics, 2017The transport of drugs across the blood-brain barrier is challenging. The use of peptide sequences derived from viruses with a central nervous system (CNS) tropism is one elegant option.
Mira Oswald, S. Geissler, A. Goepferich
semanticscholar +1 more source
2003
Publisher Summary This chapter reviews the rabies virus structure, its molecular composition and morphology, its genome organization, and its genetic relationship to the structural proteins of the virus. The chapter discusses the current knowledge of the virus's life cycle (attachment, penetration, replication, assembly, and egress) in susceptible ...
openaire +4 more sources
Publisher Summary This chapter reviews the rabies virus structure, its molecular composition and morphology, its genome organization, and its genetic relationship to the structural proteins of the virus. The chapter discusses the current knowledge of the virus's life cycle (attachment, penetration, replication, assembly, and egress) in susceptible ...
openaire +4 more sources
Apoptosis and rabies virus neuroinvasion
Biochimie, 2003Rabies virus (RV) causes a non-lytic infection of neurons leading to a fatal myeloencephalitis in mammals including humans. By comparing the infection of the nervous system of mice by a highly pathogenic neuroinvasive strain of RV (CVS) and by a strain of attenuated pathogenicity (PV) with restricted brain invasion, we showed that RV neuroinvasiveness ...
Monique Lafon, Leïla Baloul
openaire +3 more sources
Rabies Virus Infection and MicroRNAs
2011Endogenous RNA-silencing mechanisms have been shown to play a role in regulating viral and host processes during the course of infection. Such interactive processes may involve host cellular and/or viral-encoded microRNAs (miRNAs). Rabies is unique not only in terms of its invariably fatal course once disease signs develop, but it also has a variable ...
Aekkapol Mahavihakanont +2 more
openaire +3 more sources
Rabies Virus Infection: An Update
Journal of Neurovirology, 2003There are still many unanswered questions in the pathogenesis of rabies, but recent progress has been made. During most of the long incubation period of rabies, the virus likely remains close the site of viral entry. Centripetal spread to the central nervous system and spread within the central nervous system occur by fast axonal transport.
openaire +2 more sources