Results 111 to 120 of about 1,384,185 (280)

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

open access: yesFEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna   +4 more
wiley   +1 more source

Biology leads the race to turn sunlight into fuels [PDF]

open access: yesPhysics Today, 2017
A bacterium can be harnessed to do the job, but can that process be scaled up?
openaire   +2 more sources

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

open access: yesFEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji   +3 more
wiley   +1 more source

Coronary heart disease, chronic inflammation, and pathogenic social hierarchy: a biological limit to possible reductions in morbidity and mortality [PDF]

open access: yesarXiv, 2003
We suggest that a particular form of social hierarchy, which we characterize as 'pathogenic', can, from the earliest stages of life, exert a formal analog to evolutionary selection pressure, literally writing a permanent developmental image of itself upon immune function as chronic vascular inflammation and its consequences.
arxiv  

Closing achievement gaps with a utility-value intervention: Disentangling race and social class.

open access: yesJournal of Personality and Social Psychology, 2016
Many college students abandon their goal of completing a degree in science, technology, engineering, or math (STEM) when confronted with challenging introductory-level science courses.
J. Harackiewicz   +4 more
semanticscholar   +1 more source

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

open access: yesFEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki   +11 more
wiley   +1 more source

Accuracy and reproducibility of a single‐pose image‐to‐robot registration method for mobile C‐arm cone beam CT guided histotripsy

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Histotripsy is a focal tumor therapy that utilizes focused ultrasound (US) to mechanically destroy tissue. To overcome visualization limitations of diagnostic US‐guidance, C‐arm cone beam CT (CBCT)‐guided histotripsy is being developed, for which a mobile C‐arm could increase accessibility. CBCT‐guided histotripsy uses a phantom with a
Grace M. Minesinger   +5 more
wiley   +1 more source

CSF Biomarker‐Based Cognitive Trajectories in Parkinson's Disease‐Subjective Cognitive Decline

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive complaints without objective cognitive impairment in Parkinson's Disease, termed Parkinson's Disease‐Subjective Cognitive Decline (PD‐SCD), have been associated with cognitive decline. However, its progression is heterogeneous, highlighting the need for improved identification of patients at greater risk for deterioration ...
Jon Rodriguez‐Antiguedad   +7 more
wiley   +1 more source

Evolutionary Dynamics of Cultural Memes and Application to Massive Movie Data [PDF]

open access: yesarXiv, 2019
The profound impact of Darwin's theory of evolution on biology has led to the acceptance of the theory in many complex systems that lie well beyond its original domain. Culture is one example that also exhibits key Darwinian evolutionary properties: Differential adoption of cultural variants (variation and selection), new entities imitating older ones (
arxiv  

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